Evidence map›Paper›PMID 40003515›Full record

ArticleInternational journal of environmental research and public health2025

Developing an Ecotoxicological Classification for Frequently Used Drugs in Primary Care.

Tiphaine Charmillot, Nathalie Chèvre, Nicolas Senn

Abstract read
In one paragraph

Article in International journal of environmental research and public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Tiphaine CharmillotDepartment of Family Medicine, Unisanté, University of Lausanne, 1015 Lausanne, Switzerland.ORCID 0009-0007-1641-512X
Nathalie ChèvreFaculty of Geosciences and Environment, University of Lausanne, 1015 Lausanne, Switzerland.
Nicolas SennDepartment of Family Medicine, Unisanté, University of Lausanne, 1015 Lausanne, Switzerland.ORCID 0000-0002-9986-3249

Funding

Solis Grant (CHUV Foundation)the Faculty of Geosciences and Environment of the University of Lausanne (University of Lausanne)
6 · The paper itself

Abstract

Most drugs excreted in urine are not filtered by wastewater treatment plants and end up in aquatic systems. At concentrations measured in waters, toxic effects on species have been described. Second, most of the drug consumption is attributable to primary care prescriptions. We thus present here, an ecotoxicity classification of the most sold drugs in primary care in Switzerland. Three datasets were combined: (1) surveyed ecotoxic drugs by the Swiss National Surface Water Quality Monitoring Programme and its European equivalent, (2) the top 50 drugs by sale in primary care in Switzerland, and (3) active pharmaceutical ingredient (API) concentrations in Lake Geneva and the rivers of the canton of Vaud between 2017 and 2022. We classified APIs into five categories from the safest to the least safe: (1) APIs found in concentrations (C) <10× their environmental quality standard (EQS·10

Indexed as

EcotoxicologyPrimary Health CareWater Pollutants, ChemicalEnvironmental MonitoringPharmaceutical PreparationsRiversSwitzerlandPharmaceutical PreparationsWater Pollutants, ChemicalAPIdrug prescribingecotoxicologyprimary caresurface water

Identifiers

PMID40003515
PMCPMC11855898

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.