Evidence map›Paper›PMID 40003350›Full record

ArticleChildren (Basel, Switzerland)2025

Incidence and Characteristics of Pediatric Eosinophilic Esophagitis: A Midwestern State Analysis.

Jose L Zamora-Sifuentes, Andrew Rorie, Sharad Kunnath, Rosemary Pauley, Andrew Huang Pacheco, Russell Hopp

Abstract read
In one paragraph

Article in Children (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jose L Zamora-SifuentesDivision of Allergy & Immunology, Department of Internal Medicine, University of Nebraska Medical Center, Omaha, NE 68198, USA.ORCID 0009-0009-5988-9928
Andrew RorieDivision of Allergy & Immunology, Department of Internal Medicine, University of Nebraska Medical Center, Omaha, NE 68198, USA.
Sharad KunnathDivision of Gastroenterology, Department of Pediatrics, Boys Town National Research Hospital, Omaha, NE 68010, USA.
Rosemary PauleyDivision of Gastroenterology, Department of Pediatrics, Boys Town National Research Hospital, Omaha, NE 68010, USA.
Andrew Huang PachecoDivision of Gastroenterology, Department of Pediatrics, Children's Nebraska, Omaha, NE 68114, USA.
Russell HoppDivision of Pulmonology, Allergy & Sleep Medicine, Department of Pediatrics, Children's Nebraska, Omaha, NE 68114, USA.ORCID 0000-0003-3931-4237

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEosinophilic esophagitis (EoE) is a chronic disease defined by esophageal dysfunction and >15 eosinophils per high-power-field on biopsy. Despite its increased incidence across the United States, studies evaluating its incidence at any state level are lacking.

methodsRecord review of pediatric patients (<18 years) newly diagnosed with EoE based on ICD coding seen at the main two pediatric gastroenterology centers in the state: Children's Nebraska (1 January 2016-31 December 2022) and Boys Town National Research Hospital (1 January 2022-31 December 2022). Data included demographics, age, and zip codes. Descriptive analysis focused on Nebraska residents.

resultsThe average point incidence of EoE between 2016 and 2022 was 10.84/100,000 inhabitants based on data from Children's Nebraska. Considering both centers, the point incidence in Nebraska for 2022 was 32.45/100,000 inhabitants. Caucasians were 3.7 times more likely to be affected and older at time of diagnosis (average 9.7 years) compared to African Americans (7.0), Hispanics (7.4), and Asians (4.4).

conclusionsThis is the first study evaluating the incidence of EoE in a specific U.S.A state. Studies at the state level are important to direct policy and interventions aiming limit its burden in communities.

Indexed as

EGIDEoEEosinophilic esophagitiseosinophilic gastrointestinal diseasespediatrics

Identifiers

PMID40003350
PMCPMC11853838

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