Evidence map›Paper›PMID 40003325›Full record

ArticleChildren (Basel, Switzerland)2025

Clinical Associations with Lenticulostriatal Vasculopathy (LSV) at Birth: A Case-Control Study.

Aikaterini Kyriakopoulou, Kyriakos Samikos, Aikaterini Kanavaki, Efthymia Alexopoulou, Maria Argyropoulou, Theodora Psaltopoulou, Christina Kanaka-Gantenbein, Argyrios Dinopoulos, Melpomene Giorgi, Anastasia Antoniadou and 4 more

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Article in Children (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

14 authors.

Aikaterini KyriakopoulouThird Department of Pediatrics, Attikon General University Hospital, National and Kapodistrian University of Athens, 124 62 Athens, Greece.
Kyriakos SamikosIaso Maternity Hospital, 151 23 Athens, Greece.
Aikaterini KanavakiIaso Maternity Hospital, 151 23 Athens, Greece.
Efthymia Alexopoulou2nd Department of Radiology, General University Hospital Attikon, School of Medicine, National and Kapodistrian University of Athens, 124 62 Athens, Greece.ORCID 0000-0001-8466-4127
Maria ArgyropoulouDepartment of Radiology, Faculty of Medicine, School of Health Sciences, University of Ioannina, 455 00 Ioannina, Greece.
Theodora PsaltopoulouDepartment of Hygiene, Epidemiology and Medical Statistics, School of Medicine, National and Kapodistrian University of Athens, 115 27 Athens, Greece.
Christina Kanaka-GantenbeinDiabetes Center, Division of Endocrinology, Diabetes, and Metabolism, First Department of Pediatrics, Agia Sophia Children's Hospital, National and Kapodistrian University of Athens, 115 27 Athens, Greece.ORCID 0000-0001-6942-6470
Argyrios DinopoulosThird Department of Pediatrics, Attikon General University Hospital, National and Kapodistrian University of Athens, 124 62 Athens, Greece.
Melpomene GiorgiThird Department of Pediatrics, Attikon General University Hospital, National and Kapodistrian University of Athens, 124 62 Athens, Greece.
Anastasia AntoniadouFourth Department of Medicine, Attikon General University Hospital, National and Kapodistrian University of Athens, 124 62 Athens, Greece.ORCID 0000-0003-0991-9198
Iliani FilippaIaso Maternity Hospital, 151 23 Athens, Greece.
Nikolaos SiafakasClinical Microbiology Laboratory, Attikon General University Hospital, 124 62 Athens, Greece.ORCID 0000-0002-0088-143X
Stylianos SerghiouProlaio, Inc., Chicago, IL 60606, USA.ORCID 0000-0002-2477-6060
Vassiliki PapaevangelouThird Department of Pediatrics, Attikon General University Hospital, National and Kapodistrian University of Athens, 124 62 Athens, Greece.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo investigate the clinical characteristics associated with the presence of LSV at birth.

designProspective 1:1 case-control study.

settingTwo tertiary neonatal units in Athens, Greece. PATIENTS: Premature neonates (≤36 weeks gestational age) who underwent cerebral ultrasound within the first 3 weeks of life, where LSV was detected.

main outcome measureAssociations between LSV and clinical characteristics at birth. Both unmatched and matched analyses stratifying the study population by gestational week were conducted. Two-sided

resultsThis study included 166 participants (83 cases and 83 controls). Neonates with LSV exhibited more concurrent cerebral findings, notably periventricular echogenicity. LSV was correlated with higher z-scores for head circumference and body length. LSV was not associated with congenital CMV.

conclusionsThis study indicated a relationship between LSV and increased head circumference and body length. Further research is warranted to explore LSV's pathophysiological mechanisms.

Indexed as

cerebral abnormalitiesCMVfoetalLSVneonatalrisk factors

Identifiers

PMID40003325
PMCPMC11853899

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