Evidence map›Paper›PMID 40003319›Full record

ReviewChildren (Basel, Switzerland)2025

Risk and Protective Factors for Obstructive Sleep Apnea Syndrome Throughout Lifespan: From Pregnancy to Adolescence.

Duilio Petrongari, Francesca Ciarelli, Paola Di Filippo, Armando Di Ludovico, Sabrina Di Pillo, Francesco Chiarelli, Giulia Maria Pellegrino, Giuseppe Francesco Sferrazza Papa, Luana Nosetti, Marina Attanasi

Abstract readReview
In one paragraph

Review in Children (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Duilio PetrongariDepartment of Pediatrics, Pediatric Allergy and Pulmonology Unit, University of Chieti-Pescara, Via Dei Vestini 5, 66100 Chieti, Italy.
Francesca CiarelliDepartment of Pediatrics, Pediatric Allergy and Pulmonology Unit, University of Chieti-Pescara, Via Dei Vestini 5, 66100 Chieti, Italy.
Paola Di FilippoDepartment of Pediatrics, Pediatric Allergy and Pulmonology Unit, University of Chieti-Pescara, Via Dei Vestini 5, 66100 Chieti, Italy.
Armando Di LudovicoDepartment of Pediatrics, Pediatric Allergy and Pulmonology Unit, University of Chieti-Pescara, Via Dei Vestini 5, 66100 Chieti, Italy.
Sabrina Di PilloDepartment of Pediatrics, Pediatric Allergy and Pulmonology Unit, University of Chieti-Pescara, Via Dei Vestini 5, 66100 Chieti, Italy.
Francesco ChiarelliDepartment of Pediatrics, Pediatric Allergy and Pulmonology Unit, University of Chieti-Pescara, Via Dei Vestini 5, 66100 Chieti, Italy.
Giulia Maria PellegrinoDepartment of Neurorehabilitation Sciences, Casa di Cura Igea, 20144 Milan, Italy.
Giuseppe Francesco Sferrazza PapaDepartment of Neurorehabilitation Sciences, Casa di Cura Igea, 20144 Milan, Italy.ORCID 0000-0002-5245-4843
Luana NosettiDepartment of Pediatrics, Pediatric Sleep Disorders Center, F. Del Ponte Hospital, Insubria University, 21100 Varese, Italy.ORCID 0000-0001-5453-724X
Marina AttanasiDepartment of Pediatrics, Pediatric Allergy and Pulmonology Unit, University of Chieti-Pescara, Via Dei Vestini 5, 66100 Chieti, Italy.ORCID 0000-0001-6513-3160

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundObstructive sleep apnea syndrome (OSAS) in children is indeed a significant and often underdiagnosed condition. The risk factors for OSAS vary across different stages of life.

objectivesIdentifying risk factors early can help in taking preventive measures to reduce the likelihood of developing OSAS, and different life stages may require different interventions.

resultsDuring pregnancy, maternal factors such as obesity, smoking, and genetic predispositions can increase the risk of OSAS, while breastfeeding serves as a protective factor. For children aged 2 to 12, adenotonsillar hypertrophy is the primary cause of airway narrowing, with other contributing factors including obesity, craniofacial abnormalities, and increased nasal resistance. In adolescence, obesity and craniofacial abnormalities remain the main risk factors.

conclusionsBy reviewing and understanding these risk factors, healthcare providers can offer more personalized and effective care, ultimately leading to better health outcomes for individuals at all stages of life.

Indexed as

adenotonsillar hypertrophyadolescencechildrenobesityobstructive sleep apnea syndromeobstructive sleep disordersprenatal sleepsleep disorders

Identifiers

PMID40003319
PMCPMC11854123

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.