Evidence map›Paper›PMID 40003295›Full record

ArticleChildren (Basel, Switzerland)2025

Outcomes of Preterm Infants Admitted to Canadian NICUs Before and During the SARS-COV Pandemic.

Marsha Campbell-Yeo, Amy Mireault, Fabiana Bacchini, Marc Beltempo, Prakesh S Shah, Lynsey Alcock, Jeannette Comeau, Justine Dol, Amy Grant, Jonathan Gubbay and 12 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Children (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors.

Marsha Campbell-YeoDalhousie University, Halifax, NS B3H 4R2, Canada.ORCID 0000-0001-6645-2809
Amy MireaultMOM-LINC Laboratory, IWK Health, Halifax, NS B3K 6R8, Canada.
Fabiana BacchiniCanadian Premature Babies Foundation, Toronto, ON M8X 1Y3, Canada.ORCID 0000-0003-4343-774X
Marc BeltempoMcGill University Health Centre-Montreal Children's Hospital, Montreal, QC H4A 3J1, Canada.
Prakesh S ShahMount Sinai Hospital, Toronto, ON M5G 1X5, Canada.ORCID 0000-0002-9920-0488
Lynsey AlcockMOM-LINC Laboratory, IWK Health, Halifax, NS B3K 6R8, Canada.
Jeannette ComeauIWK Health, Halifax, NS B3K 6R8, Canada.
Justine DolIWK Health, Halifax, NS B3K 6R8, Canada.ORCID 0000-0002-8928-7647
Amy GrantMaritime SPOR Support Unit, Halifax, NS B3H 0A2, Canada.ORCID 0000-0003-3605-0934
Jonathan GubbayBC Children's Hospital, Vancouver, BC V6H 3N1, Canada.ORCID 0000-0003-0026-3786
Brianna HughesMOM-LINC Laboratory, IWK Health, Halifax, NS B3K 6R8, Canada.
Amos HundertIWK Health, Halifax, NS B3K 6R8, Canada.
Darlene InglisIWK Health, Halifax, NS B3K 6R8, Canada.
Yasmin LalaniCanadian Premature Babies Foundation, Toronto, ON M8X 1Y3, Canada.
Morgan MacNeilDalhousie University, Halifax, NS B3H 4R2, Canada.
Thuy Mai LuuDépartement de Pédiatrie, Centre Hospitalier Universitaire Sainte-Justine, Montréal, QC H3T 1C5, Canada.ORCID 0000-0003-2222-186X
Souvik MitraBC Children's Hospital, Vancouver, BC V6H 3N1, Canada.
Michael NarveyDepartment of Pediatrics, Children's Hospital Research Institute of Manitoba, Winnipeg, MB R3E 3P4, Canada.ORCID 0000-0002-5863-4212
Karel O'BrienMount Sinai Hospital, Toronto, ON M5G 1X5, Canada.ORCID 0000-0002-0900-7749
Paula RobesonChildren's Healthcare Canada, Ottawa, ON K2A 3W9, Canada.
Michelle ScienceSick Kids Hospital, Toronto, ON M5G 1E8, Canada.
Canadian Neonatal Network Cnn Investigators

Funding

CIHR 464929
6 · The paper itself

Abstract

backgroundTo better elucidate the impact of the SARS-COV pandemic on neonatal outcomes, we compared the health outcomes of infants born preterm requiring care in a Canadian NICU before and during the SARS-COV pandemic.

methodsUsing a retrospective cohort study, infants born between 23 and 32 weeks gestation who were admitted to tertiary Canadian NICUs before and during the pandemic were included. A total of 7280 infants were in the pre-pandemic cohort (admitted 1 April 2018-31 December 2019), and 7088 infants were in the pandemic cohort (admitted 1 April 2020-31 December 2021). The primary outcomes included major morbidity or mortality rates. Care strategies and treatments were compared across the two periods. The relative risk (RR) for the pandemic period, compared to the pre-pandemic period, was calculated using a Poisson regression model, adjusted for identified risk factors.

resultsThere were no significant differences in infant characteristics between the pre-pandemic and pandemic cohorts. The risk of mortality or major morbidity was comparable before and during the pandemic (37% pre-pandemic, 36% pandemic; RR = 1.01, 95% CI 0.92, 1.01). Individual risks for morbidity and mortality did not differ significantly between periods. There was a clinically significant decline in the receipt of the mothers' own milk exclusively at discharge during the pandemic (45% before and 37% during; RR 0.85, 95% CI 0.68, 1.06).

conclusionsThere were no significant differences in major morbidity or mortality rates in preterm infants between pre-pandemic and pandemic cohorts in Canadian NICUs.

Indexed as

health outcomesneonatal outcomespretermSARS-COV

Identifiers

PMID40003295
PMCPMC11854698

What OpenQuestion holds

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LicenceCC BY
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.