Evidence map›Paper›PMID 40003265›Full record

ArticleChildren (Basel, Switzerland)2025

Multidisciplinary Management of Acute Tetraparesis in an Infant with Achondroplasia, with a Focus on Anesthetic Strategies: A Case Report.

Barbora Nedomová, Robert Chrenko, Salome Jakešová, Petra Zahradníková, Martin Hanko, Ľubica Tichá

Abstract readCase Reports
In one paragraph

Article in Children (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Foramen magnum decompression in infants and children with achondroplasia: clinical outcomes from a 15-patient surgical series.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Barbora NedomováDepartment of Pediatric Anesthesiology and Intensive Care, Faculty of Medicine, Comenius University, Faculty of Medicine, Slovak Medical University and National Institute of Children's Diseases, 833 40 Bratislava, Slovakia.ORCID 0000-0003-2724-3662
Robert ChrenkoFaculty of Medicine, Slovak Medical University, 831 01 Bratislava, Slovakia.
Salome JakešováDepartment of Radiology, National Institute of Children's Diseases, 833 40 Bratislava, Slovakia.
Petra ZahradníkováDepartment of Pediatric Surgery, Faculty of Medicine, Comenius University and National Institute of Children's Diseases, 833 40 Bratislava, Slovakia.
Martin HankoDepartment of Neurological and Spinal Surgery, Penta Hospitals Bory, 841 03 Bratislava, Slovakia.
Ľubica TicháDepartment of Pediatrics, Faculty of Medicine, Comenius University and National Institute of Children's Diseases, 833 40 Bratislava, Slovakia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

objectivesThis report details a rare instance of an infant with achondroplasia developing acute tetraparesis after a cervical whiplash injury, highlighting key multidisciplinary management considerations and specific anesthetic strategies to mitigate potential risks. CASE PRESENTATION: A 1-year-old boy with achondroplasia presented with acute tetraparesis after a whiplash injury. Initial craniocervical computed tomography demonstrated a reduced volume of the posterior fossa, foramen magnum stenosis, and ventriculomegaly, without any fractures or dislocations. Moreover, magnetic resonance imaging (MRI) revealed pathological signal changes in the medulla oblongata, cervical spinal cord in segments C1 and C2, and the posterior atlantoaxial ligament. After initial conservative therapy and head immobilization using a soft cervical collar, partial remission of the tetraparesis was achieved. Two weeks post-injury, microsurgical posterior fossa decompression extending to the foramen magnum and C1 laminectomy was performed under general anesthesia with intraoperative neuromonitoring. Following an unsuccessful intubation attempt using a fiberoptic bronchoscope, successful airway management was achieved using a combined technique incorporating video laryngoscopy. Venous access was secured under ultrasound guidance. The patient exhibited complete remission of neurological symptoms by the third postoperative month during follow-up.

conclusionsThis case report underscores the crucial need for a multidisciplinary approach in managing children with achondroplasia, especially with foramen magnum stenosis and complex cervical spine injuries. Anesthetic management required meticulously planned airway strategies using advanced techniques like video laryngoscopy and fiberoptic bronchoscopy to reduce airway risks. It also highlights the importance of conservative therapy paired with timely neurosurgical intervention, resulting in the patient's full recovery.

Indexed as

achondroplasiaanesthesiacervical injuryforamen magnum stenosisinfant

Identifiers

PMID40003265
PMCPMC11854683

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.