Evidence map›Paper›PMID 40003040›Full record

ArticleAnimals : an open access journal from MDPI2025

Brown Algae Polysaccharides Alleviate Diquat-Induced Oxidative Stress in Piglets and IPEC-J2 Cells via Nrf2/ARE Signaling Pathway.

Chunjie Hou, Zirou Yu, Chenyu Shi, Ya Huang, Hu Liu

Abstract read
In one paragraph

Article in Animals : an open access journal from MDPI, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Effects ofAnimals : an open access journal from MDPI · 2026
    Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Chunjie HouCollege of Animal Science & Technology, China Agricultural University, No. 2 Yuanmingyuan West Road, Beijing 100193, China.
Zirou YuCollege of Animal Science & Technology, China Agricultural University, No. 2 Yuanmingyuan West Road, Beijing 100193, China.
Chenyu ShiCollege of Animal Science & Technology, China Agricultural University, No. 2 Yuanmingyuan West Road, Beijing 100193, China.
Ya HuangCollege of Animal Science & Technology, China Agricultural University, No. 2 Yuanmingyuan West Road, Beijing 100193, China.
Hu LiuCollege of Animal Science & Technology, China Agricultural University, No. 2 Yuanmingyuan West Road, Beijing 100193, China.

Funding

National Natural Science Foundation of China 32102587National Natural Science Foundation of China U22A20514Shaanxi Provincial Land Engineering Construction Group Co. 202205510410747the National Key Research and Development Program of China 2021YFD1300201the Natural Science Foundation of Shandong Province of China ZR2021QC016
6 · The paper itself

Abstract

This study investigated the effect of Brown algae polysaccharides (BAPs) on diquat-induced oxidative stress in piglets and IPEC-J2 cells through Nrf2/ARE signaling pathway. In the in vivo model, 24 male piglets of the Duroc × Landrace × Large White breed were selected and divided into 4 groups (n = 6), including the CON group (basal diet), DIQ group (10 mg/kg Diquat), BAP group (1000 mg/kg BAP), and BAP+DIQ group (1000 mg/kg BAP + 10 mg/kg Diquat). Compared with the DIQ group, BAP improved growth performance and the BAP+DIQ group reduced the levels of IL-1β, IL-6, TNF-α, and DAO in plasma, increased VH and VCR, improved jejunal tissue morphology, decreased MDA levels, and increased T-AOC (

Indexed as

antioxidant capacitybrown algae polysaccharidesIPEC-J2 cellsNrf2/ARE signaling pathwaypiglets

Identifiers

PMID40003040
PMCPMC11852254

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.