Evidence map›Paper›PMID 40002984›Full record

ArticleAnimals : an open access journal from MDPI2025

Identification of Differentially Expressed Genes in the Hypothalamus of Broilers Under Heat Stress Using Transcriptome Analysis.

Xiaofang He, Bingbing Ma, Lin Zhang, Feng Gao

Abstract read
In one paragraph

Article in Animals : an open access journal from MDPI, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Xiaofang HeJinling Institute of Science and Technology, College of Animal Science and Food Engineering, No. 99, Hongjing Avenue, Jiangning District, Nanjing 211169, China.
Bingbing MaCollege of Smart Animal Husbandry, College of Biology and Food, Shangqiu Normal University, Shangqiu 476000, China.ORCID 0000-0002-8987-9968
Lin ZhangCollege of Animal Science and Technology, Nanjing Agricultural University, No. 1 Weigang, Nanjing 210095, China.ORCID 0000-0003-1555-1086
Feng GaoCollege of Animal Science and Technology, Nanjing Agricultural University, No. 1 Weigang, Nanjing 210095, China.

Funding

Jiangsu Province Industry-University-Research Project BY2022605Natural Science Foundation of Jiangsu Province BK20240222
6 · The paper itself

Abstract

The hypothalamus is the advanced center that regulates visceral activities under the cerebral cortex. It plays some key roles, such as regulating body temperature, assessing feed intake, and balancing blood glucose and endocrine gland activities. Heat stress is known to trigger a series of detrimental consequences, prominently featuring a reduction in feed intake, an elevation in body temperature, and other related phenomena. To understand the mechanisms of how heat stress affects the function of the hypothalamus, broilers were allocated to three groups: the normal control (NC) group, the heat-stress (HS) group, and the pair-fed (PF) group. The PF group was established with the aim of eliminating the confounding effect of reduced feed intake. The trial lasted for two weeks, from the age of 28 to 42 d. A total of 280 differential expressed genes (DEGs) were identified (

Indexed as

broilerheat stresshypothalamustranscriptome analysis

Identifiers

PMID40002984
PMCPMC11852300

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.