Evidence map›Paper›PMID 40002913›Full record

ArticleBiomedicines2025

Assessing the Clinical Relevance of Soluble PD-1 and PD-L1: A Multi-Cohort Study Across Diverse Tumor Types and Prognostic Implications.

Nikolay E Kushlinskii, Olga V Kovaleva, Alexei N Gratchev, Alexander A Alferov, Yurii B Kuzmin, Nikolai Y Sokolov, Dmitry A Tsekatunov, Irina B Ryzhavskaya, Igor N Kuznetsov, Dmitry N Kushlinskii and 2 more

Abstract read
In one paragraph

Article in Biomedicines, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. PD-L1Biomarker research · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. mRNA Isoforms and Variants in Health and Disease.International journal of molecular sciences · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Nikolay E KushlinskiiN.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of the Russian Federation, 115478 Moscow, Russia.
Olga V KovalevaN.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of the Russian Federation, 115478 Moscow, Russia.ORCID 0000-0001-6132-9924
Alexei N GratchevN.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of the Russian Federation, 115478 Moscow, Russia.ORCID 0000-0003-2137-1866
Alexander A AlferovN.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of the Russian Federation, 115478 Moscow, Russia.
Yurii B KuzminN.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of the Russian Federation, 115478 Moscow, Russia.
Nikolai Y SokolovN.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of the Russian Federation, 115478 Moscow, Russia.
Dmitry A TsekatunovRegional State Budgetary Healthcare Institution of Khabarovsk Territory, Regional Clinical Oncology Center, 680042 Khabarovsk, Russia.ORCID 0009-0007-1561-9681
Irina B RyzhavskayaRegional State Budgetary Healthcare Institution of Khabarovsk Territory, Regional Clinical Oncology Center, 680042 Khabarovsk, Russia.
Igor N KuznetsovMinistry of Health of the Russian Federation, Russian University of Medicine, 127473 Moscow, Russia.
Dmitry N KushlinskiiRegional State Budgetary Healthcare Institution of Khabarovsk Territory, Regional Clinical Oncology Center, 680042 Khabarovsk, Russia.
Zaman Z MamedliN.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of the Russian Federation, 115478 Moscow, Russia.
Ivan S StilidiN.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of the Russian Federation, 115478 Moscow, Russia.

Funding

Russian Science Foundation 24-15-00356
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

cancer biomarkersprognosissPD-1sPD-L1tumor progression

Identifiers

PMID40002913
PMCPMC11852959

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.