Evidence map›Paper›PMID 40002869›Full record

ReviewBiomedicines2025

The Tight Relationship Between the Tumoral Microenvironment and Radium-223.

Miriam Conte, Miriam Tomaciello, Maria Silvia De Feo, Viviana Frantellizzi, Francesco Marampon, Flaminia De Cristofaro, Giuseppe De Vincentis, Luca Filippi

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Biomedicines, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Radium - from discovery to the present day - narrative review.Clinical and experimental medicine · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Miriam ConteDepartment of Radiological Sciences, Oncology and Anatomical Pathology, Sapienza, "Sapienza" University of Rome, 00161 Rome, Italy.ORCID 0000-0002-1677-4858
Miriam TomacielloDepartment of Radiological Sciences, Oncology and Anatomical Pathology, Sapienza, "Sapienza" University of Rome, 00161 Rome, Italy.
Maria Silvia De FeoDepartment of Radiological Sciences, Oncology and Anatomical Pathology, Sapienza, "Sapienza" University of Rome, 00161 Rome, Italy.ORCID 0000-0003-3216-4838
Viviana FrantellizziDepartment of Radiological Sciences, Oncology and Anatomical Pathology, Sapienza, "Sapienza" University of Rome, 00161 Rome, Italy.ORCID 0000-0003-3497-4236
Francesco MaramponDepartment of Radiological Sciences, Oncology and Anatomical Pathology, Sapienza, "Sapienza" University of Rome, 00161 Rome, Italy.
Flaminia De CristofaroDepartment of Radiological Sciences, Oncology and Anatomical Pathology, Sapienza, "Sapienza" University of Rome, 00161 Rome, Italy.
Giuseppe De VincentisDepartment of Radiological Sciences, Oncology and Anatomical Pathology, Sapienza, "Sapienza" University of Rome, 00161 Rome, Italy.ORCID 0000-0003-4690-1528
Luca FilippiDepartment of Biomedicine and Prevention, University of Rome "Tor Vergata", Via Montpellier 1, 00133 Rome, Italy.ORCID 0000-0003-4423-5496

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Radium-223 (

Indexed as

abirateronealpha-emitterBRCAchemotherapyhormonal therapyosteoblastsPARPprostate cancerradium-223tumor microenvironment

Identifiers

PMID40002869
PMCPMC11853176

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.