Evidence map›Paper›PMID 40002753›Full record

ArticleBiomedicines2025

Investigation of UCHL3 and HNMT Gene Polymorphisms in Greek Patients with Type 2 Diabetes Mellitus and Diabetic Retinopathy.

Konstantinos Flindris, Vivian Lagkada, Aikaterini Christodoulou, Maria Gazouli, Marilita Moschos, Georgios Markozannes, George Kitsos

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Article in Biomedicines, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Konstantinos FlindrisDepartment of Ophthalmology, University General Hospital of Ioannina, 45500 Ioannina, Greece.ORCID 0009-0001-9234-5430
Vivian LagkadaLaboratory of Biology, Department of Basic Medical Sciences, Medical School, National and Kapodistrian University of Athens, 11527 Athens, Greece.
Aikaterini ChristodoulouDepartment of Ophthalmology, University General Hospital of Ioannina, 45500 Ioannina, Greece.
Maria GazouliLaboratory of Biology, Department of Basic Medical Sciences, Medical School, National and Kapodistrian University of Athens, 11527 Athens, Greece.ORCID 0000-0002-3295-6811
Marilita Moschos1st Department of Ophthalmology, University of Athens, 11527 Athens, Greece.
Georgios MarkozannesDepartment of Hygiene and Epidemiology, Medical School, University of Ioannina, 45500 Ioannina, Greece.ORCID 0000-0001-8481-579X
George KitsosDepartment of Ophthalmology, University General Hospital of Ioannina, 45500 Ioannina, Greece.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

objectivesRecent studies have shed light on the association between genetic factors and diabetic retinopathy (DR) onset and progression. The purpose of our study was to investigate the association between rs4885322 single-nucleotide polymorphism (SNP) of the MATERIALS AND

methodsIn our case-control study, we included 85 T2DM patients with DR and 71 T2DM patients without DR (NDR), matched by ethnicity and gender. Demographic and clinical data of all patients were collected, and then patients went through a complete ophthalmological examination and were genotyped for rs4885322 SNP of

resultsNo significant differences in demographic and clinical data were observed between the DR and the NDR group (

conclusionsThe rs4885322 SNP of the

Indexed as

diabetes mellitusdiabetic retinopathyHNMTrs11558538rs4885322UCHL3

Identifiers

PMID40002753
PMCPMC11852632

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