Evidence map›Paper›PMID 40002728›Full record

ArticleBiomedicines2025

Linear and Non-Linear Optimal Control Methods to Determine the Best Chemotherapy Schedule for Most Effectively Inhibiting Tumor Growth.

Sotirios G Liliopoulos, George S Stavrakakis, Konstantinos S Dimas

Abstract read
In one paragraph

Article in Biomedicines, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Dose-response : a publication of International Hormesis Society
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Sotirios G LiliopoulosSchool of Electrical and Computer Engineering, Technical University of Crete, 731 00 Chania, Greece.ORCID 0000-0002-7338-977X
George S StavrakakisSchool of Electrical and Computer Engineering, Technical University of Crete, 731 00 Chania, Greece.
Konstantinos S DimasDepartment of Pharmacology, Faculty of Medicine, University of Thessaly, 415 00 Larissa, Greece.ORCID 0000-0001-7481-9148

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

chemotherapycomputationally optimized patient-centered chemotherapylinear autoregressive with exogenous inputs (ARX)linear quadratic regulator (LQR)pancreatic ductal adenocarcinoma (PDAC)side effects minimizationstate-depended Riccati equation (SDRE)tumor growth inhibition (TGI) mathematical modeling

Identifiers

PMID40002728
PMCPMC11852421

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.