ReviewDiagnostics (Basel, Switzerland)2025
Unplanned Excision in Soft Tissue Sarcoma: Current Knowledge and Remaining Gaps.
Review in Diagnostics (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- Limb-Sparing Resection with Prophylactic Tibial Fixation and Medial Gastrocnemius Flap Reconstruction for Recurrent Leiomyosarcoma in a Previously Irradiated Leg: A Case Report.Reports (MDPI) · 2026Article
- Article
- Is delayed three-month re-excision safe for patients who have undergone unplanned excision of soft tissue sarcomas?Journal of orthopaedic surgery and research · 2026Article
- Reconstruction after unplanned excisions of soft tissue sarcomas using intraoperative extracorporeal autogenous irradiated bone and tendon grafts: a report of three cases.World journal of surgical oncology · 2026Article
- Organizing Care Matters: Fragmented Pathways Double Early Local Recurrence Risk in Sarcoma.Cancers · 2026Article
- Leiomyosarcomas of the Great Saphenous Vein: Diagnostic and Therapeutic Strategies to Prevent Unplanned Excisions and Improve Oncologic, Functional, and Psychological Outcomes.Diseases (Basel, Switzerland) · 2025Article
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Authors and funding
2 authors.
Funding
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Abstract
Soft tissue sarcoma (STS) is a rare and heterogeneous disease, which can result in surgeons not considering STS as a differential diagnosis when they encounter a lump. However, unplanned excision (UE) often occurs in nonspecialized sarcoma centers. Before re-excision (RE) after UE, radiological examinations such as magnetic resonance imaging (MRI) should be performed to determine the surgical margin and conduct a pathological evaluation of the UE. However, differentiating between residual tumor and postsurgical changes remains challenging because of the presence of postoperative edema, hematoma, and seroma on MRI. Propensity score matching analysis showed that patients with STS who underwent RE after UE did not have higher mortality or local recurrence rates than those who underwent planned excision (PE), while RE often requires reconstruction procedures. From the patient's perspective, one operation (PE) is better than two (UE and RE) because it reduces hospital stays and time away from work. Continuous education about STS is necessary for all surgeons to reduce the incidence of UE.
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Registered trials
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