Evidence map›Paper›PMID 40002456›Full record

ArticleBrain sciences2025

Ouabain Counteracts Retinal Ganglion Cell Death Through Modulation of BDNF and IL-1 Signaling Pathways.

Amanda Candida da Rocha Oliveira, Camila Saggioro Figueiredo, Ícaro Raony, Juliana Salles Von-Held-Ventura, Marcelo Gomes Granja, Thalita Mázala-de-Oliveira, Vinícius Henrique Pedrosa-Soares, Aline Araujo Dos Santos, Elizabeth Giestal-de-Araujo

Abstract read
In one paragraph

Article in Brain sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Amanda Candida da Rocha OliveiraDepartment of Neurobiology and Program of Neurosciences, Institute of Biology, Federal Fluminense University, Niteroi 24020-141, Brazil.
Camila Saggioro FigueiredoDepartment of Neurobiology and Program of Neurosciences, Institute of Biology, Federal Fluminense University, Niteroi 24020-141, Brazil.ORCID 0000-0001-5262-231X
Ícaro RaonyInstitute of Medical Biochemistry Leopoldo de Meis, Federal University of Rio de Janeiro, Rio de Janeiro 21941-902, Brazil.ORCID 0000-0002-7037-5794
Juliana Salles Von-Held-VenturaDepartment of Neurobiology and Program of Neurosciences, Institute of Biology, Federal Fluminense University, Niteroi 24020-141, Brazil.
Marcelo Gomes GranjaResearch, Innovation, and Surveillance Center for COVID-19 and Health Emergencies, Oswaldo Cruz Foundation, Rio de Janeiro 21040-360, Brazil.ORCID 0000-0001-6243-0768
Thalita Mázala-de-OliveiraDepartment of Neurobiology and Program of Neurosciences, Institute of Biology, Federal Fluminense University, Niteroi 24020-141, Brazil.
Vinícius Henrique Pedrosa-SoaresDepartment of Neurobiology and Program of Neurosciences, Institute of Biology, Federal Fluminense University, Niteroi 24020-141, Brazil.
Aline Araujo Dos SantosNational Institute of Science and Technology on Neuroimmunomodulation-INCT-NIM, Oswaldo Cruz Foundation, Rio de Janeiro 21041-250, Brazil.ORCID 0000-0002-4199-9821
Elizabeth Giestal-de-AraujoDepartment of Neurobiology and Program of Neurosciences, Institute of Biology, Federal Fluminense University, Niteroi 24020-141, Brazil.

Funding

Coordenação de Aperfeicoamento de Pessoal de Nível Superior N/AFundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro N/ANational Council for Scientific and Technological Development N/ANational Institute of Science and Technology on Neuroimmunomodulation (INCT-NIM) N/A
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

brain-derived neurotrophic factorcytokinegrowth factorinterleukin-1βmatrix metalloproteinase-9neuroprotectionouabainretinal ganglion cellsteroid hormonetumor necrosis factor

Identifiers

PMID40002456
PMCPMC11853102

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.