Evidence map›Paper›PMID 40002410›Full record

ArticleAntioxidants (Basel, Switzerland)2025

Spermidine Supplementation Effectively Improves the Quality of Mouse Oocytes After Vitrification Freezing.

Li Wang, Weijian Li, Yalan Liu, Airixiati Dilixiati, Zhanzhan Chang, Yibai Liang, Yuhan Wang, Xiuling Ma, Ling Tang, Zhi He and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Li WangXinjiang Key Laboratory of Equine Breeding and Exercise Physiology, College of Animal Science, Xinjiang Agricultural University, Urumqi 830052, China.
Weijian LiXinjiang Key Laboratory of Equine Breeding and Exercise Physiology, College of Animal Science, Xinjiang Agricultural University, Urumqi 830052, China.ORCID 0009-0000-1043-955X
Yalan LiuXinjiang Key Laboratory of Equine Breeding and Exercise Physiology, College of Animal Science, Xinjiang Agricultural University, Urumqi 830052, China.
Airixiati DilixiatiXinjiang Key Laboratory of Equine Breeding and Exercise Physiology, College of Animal Science, Xinjiang Agricultural University, Urumqi 830052, China.
Zhanzhan ChangXinjiang Key Laboratory of Equine Breeding and Exercise Physiology, College of Animal Science, Xinjiang Agricultural University, Urumqi 830052, China.
Yibai LiangXinjiang Key Laboratory of Equine Breeding and Exercise Physiology, College of Animal Science, Xinjiang Agricultural University, Urumqi 830052, China.
Yuhan WangXinjiang Key Laboratory of Equine Breeding and Exercise Physiology, College of Animal Science, Xinjiang Agricultural University, Urumqi 830052, China.
Xiuling MaXinjiang Key Laboratory of Equine Breeding and Exercise Physiology, College of Animal Science, Xinjiang Agricultural University, Urumqi 830052, China.
Ling TangXinjiang Key Laboratory of Equine Breeding and Exercise Physiology, College of Animal Science, Xinjiang Agricultural University, Urumqi 830052, China.
Zhi HeXinjiang Key Laboratory of Equine Breeding and Exercise Physiology, College of Animal Science, Xinjiang Agricultural University, Urumqi 830052, China.
Yuan ZhangXinjiang Key Laboratory of Equine Breeding and Exercise Physiology, College of Animal Science, Xinjiang Agricultural University, Urumqi 830052, China.
Xuguang WangXinjiang Key Laboratory of Equine Breeding and Exercise Physiology, College of Animal Science, Xinjiang Agricultural University, Urumqi 830052, China.

Funding

Major science and technology projects of Xinjiang Uygur Autonomous Region 2023A02011
6 · The paper itself

Abstract

The cryopreservation of oocytes through vitrification is imperative for the conservation of livestock germplasm resources. However, as oocytes exhibit significant oxidative stress and organelle damage following vitrification freezing, it is crucial to optimise the vitrification conditions to mitigate the deleterious effects of freezing. In this study, we demonstrated that spermidine has been showed to enhance oocyte survival after vitrification freezing (92% ± 4% vs. 82% ± 3%,

Indexed as

mitochondriaoocytesoxidative stresssingle-cell transcriptomespermidinevitrification freezing

Identifiers

PMID40002410
PMCPMC11852133

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.