Evidence map›Paper›PMID 40002391›Full record

ArticleAntioxidants (Basel, Switzerland)2025

Diabetes-Mediated STEAP4 Enhances Retinal Oxidative Stress and Impacts the Development of Diabetic Retinopathy.

Brooklyn E Taylor, Scott J Howell, Chieh Lee, Zakary Taylor, Katherine Barber, Patricia R Taylor

Abstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Ethnomedicinal validation ofFrontiers in nutrition · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Brooklyn E TaylorLouis Stokes Cleveland VA Medical Center, Cleveland, OH 44106, USA.
Scott J HowellLouis Stokes Cleveland VA Medical Center, Cleveland, OH 44106, USA.ORCID 0009-0007-8585-7765
Chieh LeeLouis Stokes Cleveland VA Medical Center, Cleveland, OH 44106, USA.ORCID 0000-0001-7857-458X
Zakary TaylorDepartment of Ophthalmology and Vision Science, Case Western Reserve University, Cleveland, OH 44106, USA.
Katherine BarberLouis Stokes Cleveland VA Medical Center, Cleveland, OH 44106, USA.
Patricia R TaylorLouis Stokes Cleveland VA Medical Center, Cleveland, OH 44106, USA.ORCID 0000-0002-1186-2074

Funding

TISSUE CULTURE AND HYBRIDOMA MODULEP30EY011373 · NEI · CASE WESTERN RESERVE UNIVERSITY · PI Irina A Pikuleva · 1997 to 2026
$17.7M
Identification of Immunomodulators for Diabetic Retinopathy TherapeuticsR01EY030487 · NEI · CASE WESTERN RESERVE UNIVERSITY · PI TAYLOR, PATRICIA R · 2020 to 2024
$2.0M
BLRD VA I01 BX006424CSRD VA I01 CX002204NEI NIH HHS P30 EY011373NEI NIH HHS R01 EY030487The Cleveland Eye Bank Foundation 2024The Ohio Lions Eye Research Foundation WRBryanVA I01 BX006424VA I01 CX002204
6 · The paper itself

Abstract

Diabetic retinopathy is the most common diabetic complication of the microvasculature and one of the leading causes of acquired vision loss worldwide. Yet, the current treatments for this blinding disease are futile to many diabetics. Accordingly, new biomarkers and therapeutics for diabetic retinopathy are needed. We discovered that

Indexed as

diabetic retinopathyoxidative stressSTEAP4

Identifiers

PMID40002391
PMCPMC11851923

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.