Evidence map›Paper›PMID 40002332›Full record

ArticleAntioxidants (Basel, Switzerland)2025

Macroporous Resin Recovery of Antioxidant Polyphenol Compounds from Red Onion (

Khanafina Aliya, Ha-Seong Cho, Ibukunoluwa Fola Olawuyi, Ju-Hwi Park, Ju-Ock Nam, Won-Young Lee

Abstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Antioxidant Activity and HepG2 Cytoprotection of Water-Soluble Chili Pepper Polyphenols.Plant foods for human nutrition (Dordrecht, Netherlands) · 2026
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Khanafina AliyaSchool of Food Science and Technology, Kyungpook National University, Daegu 41566, Republic of Korea.
Ha-Seong ChoSchool of Food Science and Technology, Kyungpook National University, Daegu 41566, Republic of Korea.
Ibukunoluwa Fola OlawuyiSchool of Food Science and Technology, Kyungpook National University, Daegu 41566, Republic of Korea.ORCID 0000-0003-3630-0366
Ju-Hwi ParkSchool of Food Science and Technology, Kyungpook National University, Daegu 41566, Republic of Korea.
Ju-Ock NamSchool of Food Science and Technology, Kyungpook National University, Daegu 41566, Republic of Korea.
Won-Young LeeSchool of Food Science and Technology, Kyungpook National University, Daegu 41566, Republic of Korea.ORCID 0000-0001-5850-9692

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this study, polyphenols in the crude extract (CE) from red onion peel were recovered by macroporous resin, and their antioxidant and anti-inflammatory activities were evaluated. Among the four resins screened (SP850, XAD2, XAD7HP, and XAD16N), XAD7HP showed the highest desorption and recovery ratios, and it was used to optimize polyphenol recovery through single-factor experiments. The optimal conditions were established as 1 g resin, pH 4, 25 °C, 7 h for adsorption, followed by desorption with 70% ethanol for 1 h at 25 °C. These conditions achieved 85.00% adsorption ratio, 87.10% desorption ratio, and 20.9% yield of the macroporous resin-recovered extract (MRE) from the CE. HPLC analysis revealed that rosmarinic acid, quercetin, and myricetin were major compounds in the MRE, with the content of these compounds higher (about 7-fold) compared to the CE, confirming enhanced recovery of polyphenols by macroporous resin. Moreover, FT-IR and ¹H-NMR analysis confirmed the successful recovery of these polyphenol compounds in the MRE. Furthermore, the MRE displayed significantly improved antioxidant activities (DPPH, ABTS, and FRAP) and anti-inflammatory activities (inhibition of nitric oxide synthesis and reactive oxygen species production) compared to the CE. In summary, our findings suggest that macroporous resin can effectively recover polyphenol compounds from red onion peel extract and enhance their biological activities.

Indexed as

antioxidant and anti-inflammatory activitiesmacroporous resinpolyphenol compoundsrecoveryred onion peel

Identifiers

PMID40002332
PMCPMC11852097

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.