Evidence map›Paper›PMID 40002323›Full record

ArticleAntioxidants (Basel, Switzerland)2025

From Waste to Resource: Exploring Green Approaches for Phenolics Recovery from Olive Leaves.

Paulina Tapia-Quirós, Aina Mir-Cerdà, Mercè Granados, Sonia Sentellas, Javier Saurina

Abstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. A Review ofFoods (Basel, Switzerland) · 2026
    Review
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Paulina Tapia-QuirósDepartment of Chemical Engineering and Analytical Chemistry, Universitat de Barcelona, Martí i Franquès 1-11, E08028 Barcelona, Spain.
Aina Mir-CerdàDepartment of Chemical Engineering and Analytical Chemistry, Universitat de Barcelona, Martí i Franquès 1-11, E08028 Barcelona, Spain.ORCID 0000-0002-7692-1354
Mercè GranadosDepartment of Chemical Engineering and Analytical Chemistry, Universitat de Barcelona, Martí i Franquès 1-11, E08028 Barcelona, Spain.ORCID 0000-0003-2032-3352
Sonia SentellasDepartment of Chemical Engineering and Analytical Chemistry, Universitat de Barcelona, Martí i Franquès 1-11, E08028 Barcelona, Spain.ORCID 0000-0002-5757-7236
Javier SaurinaDepartment of Chemical Engineering and Analytical Chemistry, Universitat de Barcelona, Martí i Franquès 1-11, E08028 Barcelona, Spain.ORCID 0000-0002-4892-9535

Funding

Agencia Estatal de Investigación (Ministerio de Ciencia, Innovación y Universidades, España) PID2023-147160OB-C22
6 · The paper itself

Abstract

Waste management presents a significant challenge for agri-food industries, but also an opportunity to recover valuable bioactive compounds, particularly phenolics, aligning with circular economy principles. This study compares the efficacy of conventional solvents and natural deep eutectic solvents (NADES) in extracting polyphenols from olive leaves using the scalable techniques of solid-liquid extraction (SLE) with mechanical stirring and microwave-assisted extraction (MAE). Key factors affecting extraction yield, including solvent composition, time, and temperature were investigated. Extraction efficiency was evaluated by measuring total polyphenol content (TPC) by high-performance liquid chromatography (HPLC), antioxidant capacity (FRAP assay), and individual phenolic compounds, also quantified using HPLC. Additionally, differential pulse voltammetry (DPV) was employed to evaluate the antioxidant quality of the extracts. NADES demonstrated superior extraction performance compared to conventional solvents, with the choline-glycerol system showing the highest efficiency. The combination of MAE and NADES emerged as a green and sustainable alternative to traditional methods, offering improved yield and speed. In contrast, SLE with water or ethanol/water mixtures required extended times or higher temperatures for comparable results but offered easier scalability for industrial applications.

Indexed as

agri-food waste valorizationcircular economymicrowave-assisted extractionnatural deep eutectic solventsphenolic compounds

Identifiers

PMID40002323
PMCPMC11852040

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.