Evidence map›Paper›PMID 40002318›Full record

ArticleAntioxidants (Basel, Switzerland)2025

Effect of Block Freeze Concentration on Bioactive Compound Content and Antioxidant Capacity When Applied to Peppermint (

Indira Pérez-Bermúdez, Alison Castillo-Suero, Constanza Jara-Leiva, Axel Cortés-Valdivia, Karol Rojas-Rojas, Vivian García-Rojas, Mauricio Opazo-Navarrete, María Guerra-Valle, Guillermo Petzold, Patricio Orellana-Palma

Abstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Indira Pérez-BermúdezGrupo de Crioconcentración de Alimentos y Procesos Relacionados, Departamento de Ingeniería en Alimentos, Facultad de Ciencias de la Salud y de los Alimentos, Universidad del Bío-Bío, Campus Fernando May, Av. Andrés Bello 720, Chillán 3780000, Chile.ORCID 0000-0001-9098-3511
Alison Castillo-SueroDepartamento de Ingeniería en Alimentos, Facultad de Ingeniería, Universidad de La Serena, Campus Andrés Bello, Av. Raúl Bitrán 1305, La Serena 1720010, Chile.
Constanza Jara-LeivaDepartamento de Ingeniería en Alimentos, Facultad de Ingeniería, Universidad de La Serena, Campus Andrés Bello, Av. Raúl Bitrán 1305, La Serena 1720010, Chile.
Axel Cortés-ValdiviaDepartamento de Ingeniería en Alimentos, Facultad de Ingeniería, Universidad de La Serena, Campus Andrés Bello, Av. Raúl Bitrán 1305, La Serena 1720010, Chile.
Karol Rojas-RojasDepartamento de Ingeniería en Alimentos, Facultad de Ingeniería, Universidad de La Serena, Campus Andrés Bello, Av. Raúl Bitrán 1305, La Serena 1720010, Chile.
Vivian García-RojasGrupo de Crioconcentración de Alimentos y Procesos Relacionados, Departamento de Ingeniería en Alimentos, Facultad de Ciencias de la Salud y de los Alimentos, Universidad del Bío-Bío, Campus Fernando May, Av. Andrés Bello 720, Chillán 3780000, Chile.
Mauricio Opazo-NavarreteAgriaquaculture Nutritional Genomic Center (CGNA), Temuco 4780000, Chile.
María Guerra-ValleEscuela de Nutrición y Dietética, Facultad de Ciencias Para el Cuidado de la Salud, Universidad San Sebastián, Campus Concepción, Lientur 1457, Concepción 4080871, Chile.ORCID 0000-0001-5718-3379
Guillermo PetzoldGrupo de Crioconcentración de Alimentos y Procesos Relacionados, Departamento de Ingeniería en Alimentos, Facultad de Ciencias de la Salud y de los Alimentos, Universidad del Bío-Bío, Campus Fernando May, Av. Andrés Bello 720, Chillán 3780000, Chile.ORCID 0000-0002-6924-7816
Patricio Orellana-PalmaDepartamento de Ingeniería en Alimentos, Facultad de Ingeniería, Universidad de La Serena, Campus Andrés Bello, Av. Raúl Bitrán 1305, La Serena 1720010, Chile.ORCID 0000-0002-7644-7509

Funding

Agencia Nacional de Investigación y Desarrollo de Chile FONDECYT INICIACIÓN EN INVESTIGACIÓN 2022 (Folio 11220283)
6 · The paper itself

Abstract

This research aimed to evaluate block freeze concentration (BFC) under different centrifugation conditions using response surface methodology to separate an extract from the ice fraction at three centrifugal-BFC (CBFC) cycles, obtaining in the final cycle a phenolic-rich extract. A Box-Behnken design was applied to optimize centrifugation variables, with efficiency of separation (η) selected as the response variable. The extracts were characterized in terms of physicochemical analysis, total and individual bioactive components, and antioxidant capacity. Optimal conditions (3600 rpm, 16 °C, and 14 min) resulted in η of 82%. Thus, from infusion to final cycle, the solids, total polyphenol and flavonoid contents, and antioxidant capacity exhibited from 1.81 to 6.5% (

Indexed as

antioxidant capacitybioactive compoundsfreeze concentrationinfusionMentha piperita L.physicochemical analysis

Identifiers

PMID40002318
PMCPMC11851875

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.