Evidence map›Paper›PMID 40002317›Full record

ArticleAntioxidants (Basel, Switzerland)2025

Preliminary Effects of American Elderberry Juice on Cognitive Functioning in Mild Cognitive Impairment Patients: A Secondary Analysis of Cognitive Composite Scores in a Randomized Clinical Trial.

Madison Musich, Ashley F Curtis, Bradley J Ferguson, David Drysdale, Andrew L Thomas, C Michael Greenlief, Joel I Shenker, D Q Beversdorf

Abstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Madison MusichDepartment of Psychological Sciences, University of Missouri, Columbia, MO 65201, USA.ORCID 0000-0002-0811-1878
Ashley F CurtisCollege of Nursing, University of South Florida, Tampa Bay, FL 33620, USA.ORCID 0000-0002-2311-5674
Bradley J FergusonDepartment of Neurology, University of Missouri, Columbia, MO 65201, USA.ORCID 0000-0002-1636-7849
David DrysdaleDepartments of Biology and Chemistry, St. Ambrose University, Davenport, IA 52803, USA.
Andrew L ThomasDivision of Plant Science and Technology, Southwest Research Extension and Education Center, University of Missouri, Mt. Vernon, MO 65201, USA.
C Michael GreenliefDepartment of Chemistry, University of Missouri, Columbia, MO 65201, USA.ORCID 0000-0001-6420-7375
Joel I ShenkerDepartment of Neurology, University of Missouri, Columbia, MO 65201, USA.
D Q BeversdorfDepartment of Psychological Sciences, University of Missouri, Columbia, MO 65201, USA.ORCID 0000-0002-0298-0634

Funding

The Interactions Core/Mark McintoshP50AT006273 · NCCIH · UNIVERSITY OF MISSOURI-COLUMBIA · PI LUBAHN, DENNIS B · 2010 to 2014
$7.4M
NCCIH NIH HHS P50 AT006273
6 · The paper itself

Abstract

Previous work examining dietary interventions high in polyphenols (i.e., antioxidant/anti-inflammatory properties) has shown cognitive benefits. In a prior investigation examining American elderberry juice consumption with inflammation and cognition in mild cognitive impairment (MCI), we found a trend toward better visuospatial construct flexibility in MCI patients who consumed elderberry relative to the placebo control. This study aims to further examine the preliminary effects of American elderberry juice on the cognitive domains in MCI using cognitive composite scores. MCI patients (

Indexed as

antioxidantscognitive flexibilityelderberrymild cognitive impairmentSambucus

Identifiers

PMID40002317
PMCPMC11851714

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.