Evidence map›Paper›PMID 40002199›Full record

ReviewCancers2025

Aggressive Serous Carcinomas of the Female Reproductive Tract: Cancer-Prone Cell States and Genetic Drivers.

Daryl J Phuong, Matalin G Pirtz, Coulter Q Ralston, Benjamin D Cosgrove, John C Schimenti, Andrea Flesken-Nikitin, Alexander Yu Nikitin

Abstract readReview
In one paragraph

Review in Cancers, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Daryl J PhuongDepartment of Biomedical Sciences, Cornell University, Ithaca, NY 14853, USA.ORCID 0000-0003-4049-8694
Matalin G PirtzDepartment of Biomedical Sciences, Cornell University, Ithaca, NY 14853, USA.ORCID 0000-0002-5668-3061
Coulter Q RalstonDepartment of Biomedical Sciences, Cornell University, Ithaca, NY 14853, USA.ORCID 0000-0003-2093-6482
Benjamin D CosgroveMeinig School of Biomedical Engineering, Cornell University, Ithaca, NY 14853, USA.
John C SchimentiDepartment of Biomedical Sciences, Cornell University, Ithaca, NY 14853, USA.
Andrea Flesken-NikitinDepartment of Biomedical Sciences, Cornell University, Ithaca, NY 14853, USA.ORCID 0000-0003-3017-1399
Alexander Yu NikitinDepartment of Biomedical Sciences, Cornell University, Ithaca, NY 14853, USA.ORCID 0000-0002-3729-7982

Funding

Endometrial epithelial stem cells and cancerR01CA248524 · NCI · CORNELL UNIVERSITY · PI NIKITIN, ALEXANDER Y. · 2021 to 2025
$2.1M
Cancer-prone cell states of the fallopian tubal epitheliumR01CA260115 · NCI · CORNELL UNIVERSITY · PI NIKITIN, ALEXANDER Y. · 2021 to 2025
$2.1M
Origins of Ovarian CarcinomaR01CA182413 · NCI · CORNELL UNIVERSITY · PI NIKITIN, ALEXANDER Y. · 2015 to 2019
$1.8M
Cornell Stem Cell Program NANCI NIH HHS R01 CA182413NCI NIH HHS R01 CA248524NCI NIH HHS R01 CA260115NIH HHS CA182413NIH HHS CA248524NIH HHS CA260115NSF DGE-2139899Sandra Atlas Bass Endowment for Cancer Research NA
6 · The paper itself

Abstract

In 2025, gynecological cancers are projected to account for approximately 10% of cancer-related deaths in women. High-grade serous ovarian carcinoma (HGSC) and serous endometrial carcinoma (SEC) are the most lethal gynecological cancer subtypes. Both malignancies commonly have

Indexed as

cancer-prone cell stategenetic driversovarian canceruterine cancer

Identifiers

PMID40002199
PMCPMC11852459

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.