Evidence map›Paper›PMID 40002182›Full record

ArticleCancers2025

Identifying High-Risk Patients with Advanced Midface Cancer: Personalized Surgical and Reconstructive Approach for Radical Resection.

Daniel Bula, Jakub Opyrchał, Dominik Walczak, Łukasz Krakowczyk, Adam Maciejewski

Abstract read
In one paragraph

Article in Cancers, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Daniel Bula1st Department of Oncological Surgery with a Subunit of Reconstructive and Plastic Surgery, Maria Sklodowska-Curie National Research Institute of Oncology, 44-100 Gliwice, Poland.ORCID 0000-0002-6593-3384
Jakub Opyrchał1st Department of Oncological Surgery with a Subunit of Reconstructive and Plastic Surgery, Maria Sklodowska-Curie National Research Institute of Oncology, 44-100 Gliwice, Poland.
Dominik Walczak1st Department of Oncological Surgery with a Subunit of Reconstructive and Plastic Surgery, Maria Sklodowska-Curie National Research Institute of Oncology, 44-100 Gliwice, Poland.
Łukasz Krakowczyk1st Department of Oncological Surgery with a Subunit of Reconstructive and Plastic Surgery, Maria Sklodowska-Curie National Research Institute of Oncology, 44-100 Gliwice, Poland.ORCID 0000-0002-6096-5651
Adam Maciejewski1st Department of Oncological Surgery with a Subunit of Reconstructive and Plastic Surgery, Maria Sklodowska-Curie National Research Institute of Oncology, 44-100 Gliwice, Poland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIndividually personalized reconstructive microsurgery is more and more universally recognized and applied as a one-time, part of a few, or even the only highly effective treatment of patients with locally advanced midface cancer. Among the increasing number of publications focused on this field, most present different reconstructive techniques used for a single patient (case reports), and fewer papers evaluate a group including more than 100 patients.

methodsA dataset of 119 locally advanced midface cancers in stage T

resultsIn general, the 5-year OS was 95% and 77% for the DFS, which inversely correlated with the increasing Cordeiro's type of resective defects. Local recurrence occurred in 23% of cases. Taxonomic dendrograms allow the selection of four (A-D) different case clusters. Cluster B, which characterizes a tumor size of 8-18 cm

conclusionsThe results of the present analysis have led to design algorithms for midface resection and reconstruction. However, these should not be considered obligatory but rather as a useful general guideline.

Indexed as

microvascular reconstructive surgerymidface cancertaxonomic prognostic care clusters

Identifiers

PMID40002182
PMCPMC11852440

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.