Evidence map›Paper›PMID 40002161›Full record

ArticleCancers2025

Impact of Small Area Level Deprivation on Colorectal Cancer Survival: Findings from the Regional Cancer Registry in Korea.

Seung Min Hong, Ahreum Kim, Changhoon Kim, Seunghye Jang, Dong Uk Kim, Dong Hoon Baek, Seung Hun Lee, Yu Hyeon Yi, Heeseung Park, Jonghyun Lee and 2 more

Abstract read
In one paragraph

Article in Cancers, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Seung Min HongDepartment of Internal Medicine, Pusan National University School of Medicine, Busan 49241, Republic of Korea.ORCID 0000-0002-6393-0809
Ahreum KimOffice of Public Healthcare Service, Pusan National University Hospital, Busan 49241, Republic of Korea.ORCID 0000-0002-2930-1232
Changhoon KimDepartment of Preventive Medicine, Pusan National University School of Medicine, Busan 49241, Republic of Korea.
Seunghye JangBiomedical Research Institute, Pusan National University Hospital, Busan 49241, Republic of Korea.
Dong Uk KimDivision of Gastroenterology, Department of Internal Medicine, CHA University Gumi Medical Center, Gumi 39295, Republic of Korea.
Dong Hoon BaekDepartment of Internal Medicine, Pusan National University School of Medicine, Busan 49241, Republic of Korea.ORCID 0000-0003-1512-9475
Seung Hun LeeBiomedical Research Institute, Pusan National University Hospital, Busan 49241, Republic of Korea.ORCID 0000-0002-0976-8708
Yu Hyeon YiBiomedical Research Institute, Pusan National University Hospital, Busan 49241, Republic of Korea.ORCID 0000-0002-1786-2737
Heeseung ParkBiomedical Research Institute, Pusan National University Hospital, Busan 49241, Republic of Korea.ORCID 0000-0001-9889-5217
Jonghyun LeeDepartment of Internal Medicine, Pusan National University School of Medicine, Busan 49241, Republic of Korea.ORCID 0000-0002-9752-5860
Tae In KimDepartment of Internal Medicine, Pusan National University School of Medicine, Busan 49241, Republic of Korea.ORCID 0000-0001-6068-561X
Hyun Joo LeeBiomedical Research Institute, Pusan National University Hospital, Busan 49241, Republic of Korea.ORCID 0000-0002-1223-4387

Funding

Biomedical Research Institute Grant, Pusan National University Hospital 202200450001
6 · The paper itself

Abstract

BACKGROUND/

objectivesResearch on the relationship between small-area-level deprivation and cancer survival, particularly for colorectal cancer (CRC), is lacking. Therefore, we investigated the relationship among small area-level deprivation, individual-level factors, and CRC survival using data from the Busan Regional Cancer Registry.

methodsWe analyzed 34,999 patients with CRC from the Busan Regional Cancer Registry from 2003 to 2020. The primary outcome was CRC mortality. The explanatory variables at the individual level included age, gender, cancer stage, and year of diagnosis, whereas the Deprivation Index (DI) was used at the regional level. We conducted a multilevel survival analysis with frailty to assess the impact of individual- and area-level factors on survival probabilities.

resultsIn the multilevel survival model, each unit increase in the DI at the area level was associated with a 6.6% decrease in survival probability. When applying Model 2 and deriving regional estimates using the empirical Bayesian estimation method, the graph of the DI (x-axis) against survival probability (y-axis) showed that the slope of the regional DI for the 3-year and 5-year survival probabilities increased compared with the 1-year rate across all stages of the disease. Additionally, the slopes were steeper for the distant stage than for the local or regional stages.

conclusionsSmall-area level deprivation negatively affects CRC survival, especially in distant-stage patients and those with longer disease duration.

Indexed as

colorectal cancerdeprivation indexsurvival

Identifiers

PMID40002161
PMCPMC11852685

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.