Evidence map›Paper›PMID 40002087›Full record

ArticleFoods (Basel, Switzerland)2025

Green Extraction and NMR Analysis of Bioactives from Orange Juice Waste.

Paula Scarabotto Penteado, Maria Carolina B Di-Medeiros Leal, Maria Gabriela Aparecida Carosio, Alef Dos Santos, Mateus Lodi Segatto, Daniel Petinatti Pavarini, Danielle Fernandes da Silva, Jéssica Cristina Amaral, Maria Fátima das G F da Silva, Vânia G Zuin Zeidler and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Foods (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Paula Scarabotto PenteadoDepartment of Chemistry, Federal University of São Carlos, São Carlos 13565-905, SP, Brazil.ORCID 0009-0001-6446-5654
Maria Carolina B Di-Medeiros LealDepartment of Chemistry, Federal University of São Carlos, São Carlos 13565-905, SP, Brazil.ORCID 0000-0001-5474-9728
Maria Gabriela Aparecida CarosioDepartment of Chemistry, University of Wisconsin-Madison, Madison, WI 53706, USA.
Alef Dos SantosDepartment of Chemistry, Federal University of São Carlos, São Carlos 13565-905, SP, Brazil.
Mateus Lodi SegattoDepartment of Chemistry, Federal University of São Carlos, São Carlos 13565-905, SP, Brazil.ORCID 0000-0001-9841-3257
Daniel Petinatti PavariniPerdue Animal Nutrition, Salisbury, MD 21804, USA.
Danielle Fernandes da SilvaDepartment of Chemistry, Federal University of São Carlos, São Carlos 13565-905, SP, Brazil.
Jéssica Cristina AmaralDepartment of Chemistry, Federal University of São Carlos, São Carlos 13565-905, SP, Brazil.ORCID 0000-0002-4509-259X
Maria Fátima das G F da SilvaDepartment of Chemistry, Federal University of São Carlos, São Carlos 13565-905, SP, Brazil.ORCID 0000-0002-7081-817X
Vânia G Zuin ZeidlerInstitute of Sustainable Chemistry, Leuphana University Lüneburg, 21335 Lüneburg, Germany.ORCID 0000-0003-4452-4570
Antonio G FerreiraDepartment of Chemistry, Federal University of São Carlos, São Carlos 13565-905, SP, Brazil.ORCID 0000-0003-2314-216X

Funding

CNPq - National Council for Scientific and Technological Development 001Fapesp 2014/50918-7, 17/25015-1 and 18/11409-0INCT 2014: For the biorational control of pest insects and phytopathogens 2019/10756-1 MCBML 20/07806-4 DPP
6 · The paper itself

Abstract

Brazil is a global leader in the orange industry, producing approximately one-fourth of the world's oranges and generating over 50% of the associated waste. These by-products are rich in bioactive compounds; however, their improper disposal poses environmental risks. This study employs an eco-friendly approach-microwave-assisted extraction-to recover valuable compounds from orange juice production waste. The extracted compounds were analyzed using nuclear magnetic resonance (NMR) and gas chromatography-mass spectrometry (GC-MS). Key bioactives, including D-limonene, valencene, hesperidin, and carbohydrates, were successfully identified. NMR effectively traces and semi-quantifies these compounds, while microwave-assisted extraction enables the sustainable recovery of high-purity hesperidin, confirmed by NMR (87.66%) and HPLC (84.30%) analyses.

Indexed as

circular economyenvironmental healthflavonoidsGC–MSmicrowave-assisted extraction

Identifiers

PMID40002087
PMCPMC11854020

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.