Evidence map›Paper›PMID 40002059›Full record

ArticleFoods (Basel, Switzerland)2025

Sustainable Valorization of Coffee Silverskin Waste: Pressurized Liquid Extraction of Bioactive Compounds.

Sokratis E Koskinakis, Chrysanthos Stergiopoulos, Christoforos Vasileiou, Magdalini Krokida

Abstract read
In one paragraph

Article in Foods (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Sokratis E KoskinakisLaboratory of Process Analysis and Design, School of Chemical Engineering, National Technical University of Athens, 9 Heroon Polytechniou St., Zografou Campus, 15780 Athens, Greece.ORCID 0009-0003-9282-5615
Chrysanthos StergiopoulosLaboratory of Process Analysis and Design, School of Chemical Engineering, National Technical University of Athens, 9 Heroon Polytechniou St., Zografou Campus, 15780 Athens, Greece.ORCID 0000-0001-6002-4870
Christoforos VasileiouLaboratory of Process Analysis and Design, School of Chemical Engineering, National Technical University of Athens, 9 Heroon Polytechniou St., Zografou Campus, 15780 Athens, Greece.
Magdalini KrokidaLaboratory of Process Analysis and Design, School of Chemical Engineering, National Technical University of Athens, 9 Heroon Polytechniou St., Zografou Campus, 15780 Athens, Greece.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Coffee silverskin, a by-product of the coffee roasting industry, offers significant potential for valorization due to its bioactive compound content. This study optimized the Pressurized Liquid Extraction (PLE) process for recovering phenolic compounds and caffeine from coffee silverskin. A factorial design identified the temperature and ethanol concentration as the key parameters influencing extraction yield, antioxidant capacity (TEAC), total phenolic content (TPC) and caffeine and phenolic acid contents. These factors were further optimized using a central composite design (CCD) and Response Surface Methodology (RSM). The optimal extraction conditions-140 °C and 55% ethanol-achieved a balanced enhancement across all responses: 12.1% extraction yield, 65.3 mg TE/g dry extract for antioxidant capacity, 88.4 mg GAE/g dry extract for total phenolic content, 56.7 mg caffeine/g dry extract, and 10.6 mg chlorogenic acid equivalents/g dry extract for phenolic acid content. Compared to conventional methods, the optimized PLE demonstrated superior bioactive compound recovery while employing environmentally friendly solvents. This approach underscores PLE's potential as a sustainable technology for valorizing agro-industrial by-products, contributing to both waste reduction and the development of antioxidant-rich products.

Indexed as

by-productcoffee industrypressurize liquid extractionresponse surface methodologysilverskin

Identifiers

PMID40002059
PMCPMC11853903

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.