Evidence map›Paper›PMID 40001897›Full record

ReviewBiology2025

Advances in Huntington's Disease Biomarkers: A 10-Year Bibliometric Analysis and a Comprehensive Review.

Sarah Aqel, Jamil Ahmad, Iman Saleh, Aseela Fathima, Asmaa A Al Thani, Wael M Y Mohamed, Abdullah A Shaito

Abstract readReview
In one paragraph

Review in Biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Review
  4. Article
  5. Article
  6. Review
  7. Review
  8. Review
  9. Review
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Sarah AqelMedical Research Center, Hamad Medical Corporation, Doha P.O. Box 3050, Qatar.ORCID 0009-0003-4590-509X
Jamil AhmadMedical Education, Hamad Medical Corporation, Doha P.O. Box 3050, Qatar.
Iman SalehBiological Science Program, Department of Biological and Environmental Sciences, College of Art and Science, Qatar University, Doha P.O. Box 2713, Qatar.
Aseela FathimaBiomedical Research Center (BRC), QU Health Sector, Qatar University, Doha P.O. Box 2713, Qatar.
Asmaa A Al ThaniBiomedical Research Center (BRC), QU Health Sector, Qatar University, Doha P.O. Box 2713, Qatar.
Wael M Y MohamedDepartment of Basic Medical Sciences, Kulliyyah of Medicine, International Islamic University Malaysia (IIUM), Kuantan 50728, Malaysia.ORCID 0000-0003-1317-0829
Abdullah A ShaitoBiomedical Research Center (BRC), QU Health Sector, Qatar University, Doha P.O. Box 2713, Qatar.ORCID 0000-0003-3524-7962

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neurodegenerative disorders (NDs) cause progressive neuronal loss and are a significant public health concern, with NDs projected to become the second leading global cause of death within two decades. Huntington's disease (HD) is a rare, progressive ND caused by an autosomal-dominant mutation in the huntingtin (

Indexed as

biomarkersdiffusion tensor imaging (DTI)Huntington’s diseasemicroRNAs (miRNAs)neurodegenerative disordersneurofilament light chain (NfL)preHDpremanifest HDrare diseases

Identifiers

PMID40001897
PMCPMC11852324

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.