Evidence map›Paper›PMID 40001503›Full record

ArticleBiomolecules2025

Classical Swine Fever Virus Envelope Glycoproteins E

Liyuan Zhang, Dongli Liang, Yu Tian, Jiaxin Liang, Xiaoquan Li, Cheng Liu, Jingjing Liang, Ting Rong Luo, Xiaoning Li

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomolecules, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Liyuan ZhangState Key Laboratory for Conservation and Utilization of Subtropical Agro-Bioresources, Guangxi University, Nanning 530004, China.
Dongli LiangState Key Laboratory for Conservation and Utilization of Subtropical Agro-Bioresources, Guangxi University, Nanning 530004, China.
Yu TianState Key Laboratory for Conservation and Utilization of Subtropical Agro-Bioresources, Guangxi University, Nanning 530004, China.
Jiaxin LiangState Key Laboratory for Conservation and Utilization of Subtropical Agro-Bioresources, Guangxi University, Nanning 530004, China.
Xiaoquan LiState Key Laboratory for Conservation and Utilization of Subtropical Agro-Bioresources, Guangxi University, Nanning 530004, China.
Cheng LiuState Key Laboratory for Conservation and Utilization of Subtropical Agro-Bioresources, Guangxi University, Nanning 530004, China.
Jingjing LiangState Key Laboratory for Conservation and Utilization of Subtropical Agro-Bioresources, Guangxi University, Nanning 530004, China.ORCID 0000-0002-4623-9864
Ting Rong LuoState Key Laboratory for Conservation and Utilization of Subtropical Agro-Bioresources, Guangxi University, Nanning 530004, China.
Xiaoning LiState Key Laboratory for Conservation and Utilization of Subtropical Agro-Bioresources, Guangxi University, Nanning 530004, China.

Funding

General Program of the Natural Science Foundation of Guangxi Province grant nos. 2021GXNSFAA220007 and 2017GXNSFAA198137the Major Project of the Natural Science Foundation of Guangxi Province grant no. 2023GXNSFDA026043the National Natural Science Foundation of China grant nos. 32360869, 31660722, and 31460653the Youth Fund Project of the Natural Science Foundation of Guangxi Province grant no. 2018GXNSFBA281170
6 · The paper itself

Abstract

Classical swine fever (CSF) is an acute and often fatal disease caused by CSF virus (CSFV) infection. In the present study, we investigated the transcriptional profiles of peripheral blood mononuclear cells (PBMCs) in pigs infected with CSFV. The results revealed that CSFV inhibits IFNα/β production, but up-regulates the expression of signal transducer and activator of transcription 1 (STAT1); this result was verified in vitro. Interestingly, STAT1 is typically a downstream target of IFNα/β, raising the question of how CSFV can inhibit IFNα/β expression, yet up-regulate STAT1 expression. To explore this further, we observed that UV-treated CSFV induced STAT1 expression. Our results demonstrated that CSFV E

Indexed as

Classical Swine FeverClassical Swine Fever VirusInterleukin-10STAT1 Transcription FactorViral Envelope Proteins2',5'-Oligoadenylate SynthetaseAnimalsInterferon-alphaInterferon-betaLeukocytes, MononuclearMyxovirus Resistance ProteinsSignal TransductionSwine2',5'-Oligoadenylate SynthetaseInterferon-alphaInterferon-betaInterleukin-10Myxovirus Resistance ProteinsSTAT1 Transcription FactorViral Envelope ProteinsCSFVinterleukin-10MX1OAS1STAT1surface glycoproteins

Identifiers

PMID40001503
PMCPMC11853677

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.