ArticleBiomolecules2025
Higher Levels of Serum Leptin Are Linked with a Reduction in Gait Stability: A Sex-Based Association.
Article in Biomolecules, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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5 authors.
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Abstract
Gait stability prevents falls and injuries during physical activities. Muscle strength, aging, and co-existing chronic diseases are factors that affect gait stability. Leptin is an adipokine with pro-inflammatory properties. Several reports demonstrated an association between serum leptin and a reduction in muscle strength. Given the above relationships, we hypothesized that serum leptin could be associated with gait stability. To test this, 146 apparently healthy university students were recruited. Data collection involved anthropometric measurements, physical activity (PA) data, gait parameters, and serum leptin levels. A gait instability index was derived from the percentages of double support time and walking asymmetry (WA) collected from smartphones. Females demonstrated higher leptin levels and WA despite a lower body mass index (BMI). Lower PA levels were also observed among females. Leptin levels were negatively correlated with WA, step count, and vigorous PA (
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