Evidence map›Paper›PMID 40001458›Full record

ReviewBiomolecules2025

The Versatility of Serine Proteases from Brazilian

Marcela Romanazzi, Eloise T M Filardi, Geovanna M M Pires, Marcos F Cerveja, Guilherme Melo-Dos-Santos, Isadora S Oliveira, Isabela G Ferreira, Felipe A Cerni, Norival Alves Santos-Filho, Wuelton M Monteiro and 3 more

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Biomolecules, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. BrazilianToxins · 2026
    Article
  2. Article
  3. Article
  4. Review
  5. Phospholipases ABiomolecules · 2025
    Review
  6. Procoagulant Effects ofInternational journal of molecular sciences · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Marcela RomanazziGraduate Program in Bioscience and Biotechnology Applied to Pharmacy, School of Pharmaceutical Sciences, São Paulo State University (UNESP), Araraquara 19060-900, Brazil.
Eloise T M FilardiGraduate Program in Bioscience and Biotechnology Applied to Pharmacy, School of Pharmaceutical Sciences, São Paulo State University (UNESP), Araraquara 19060-900, Brazil.ORCID 0000-0003-1566-1867
Geovanna M M PiresDepartment of Clinical Analysis, School of Pharmaceutical Sciences, São Paulo State University (UNESP), Araraquara 19060-900, Brazil.ORCID 0009-0006-8825-3708
Marcos F CervejaGraduate Program in Bioscience and Biotechnology Applied to Pharmacy, School of Pharmaceutical Sciences, São Paulo State University (UNESP), Araraquara 19060-900, Brazil.ORCID 0009-0003-7909-5099
Guilherme Melo-Dos-SantosGraduate Program in Bioscience and Biotechnology Applied to Pharmacy, School of Pharmaceutical Sciences, São Paulo State University (UNESP), Araraquara 19060-900, Brazil.
Isadora S OliveiraDepartment of Biomolecular Sciences, School of Pharmaceutical Sciences of Ribeirão Preto, University of São Paulo, Ribeirão Preto 19040-903, Brazil.ORCID 0000-0002-2036-1191
Isabela G FerreiraDepartment of Biomolecular Sciences, School of Pharmaceutical Sciences of Ribeirão Preto, University of São Paulo, Ribeirão Preto 19040-903, Brazil.ORCID 0000-0002-7424-7132
Felipe A CerniMedical School, Federal University of Roraima, Boa Vista 69310-000, Brazil.
Norival Alves Santos-FilhoGraduate Program in Bioscience and Biotechnology Applied to Pharmacy, School of Pharmaceutical Sciences, São Paulo State University (UNESP), Araraquara 19060-900, Brazil.ORCID 0000-0002-0344-6900
Wuelton M MonteiroDepartment of Teaching and Research, Dr. Heitor Vieira Dourado Tropical Medicine Foundation, Manaus 69850-000, Brazil.ORCID 0000-0002-0848-1940
José R AlmeidaSchool of Pharmacy, University of Reading, Reading RG6 6UB, UK.ORCID 0000-0002-4637-4468
Sakthivel VaiyapuriSchool of Pharmacy, University of Reading, Reading RG6 6UB, UK.ORCID 0000-0002-6006-6517
Manuela B PuccaGraduate Program in Bioscience and Biotechnology Applied to Pharmacy, School of Pharmaceutical Sciences, São Paulo State University (UNESP), Araraquara 19060-900, Brazil.ORCID 0000-0003-2594-7068

Funding

Coordenação de Aperfeicoamento de Pessoal de Nível Superior Finance Code 001Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) No. 2024/08990-4 and 2023/15381-1, MR No. 2024/01801-1, RF No. 2024/13258-0, IF No. 2023/11264-0 and IO No. 2020/13176-3Medical Research Council MR/W019353/1National Council for Scientific and Technological Development No. 305778/2023-4
6 · The paper itself

Abstract

Serine proteases are multifunctional and versatile venom components found in viper snakes, including the

Indexed as

BothropsCrotalid VenomsDrug DiscoverySerine ProteasesSnake BitesAnimalsBrazilHumansCrotalid VenomsSerine Proteasescoagulationserine proteasesnakebitevenom

Identifiers

PMID40001458
PMCPMC11852464

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.