Evidence map›Paper›PMID 40001406›Full record

ArticleAntibiotics (Basel, Switzerland)2025

Bactericidal Effect of a Novel Phage Endolysin Targeting Multi-Drug-Resistant

Sara Garcia Torres, Dirk Henrich, Rene D Verboket, Ingo Marzi, Gernot Hahne, Volkhard A J Kempf, Stephan Göttig

Abstract read
In one paragraph

Article in Antibiotics (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Sara Garcia TorresGoethe University Frankfurt, University Hospital, Institute of Medical Microbiology and Infection Control, 60596 Frankfurt am Main, Germany.
Dirk HenrichGoethe University Frankfurt, University Hospital, Department of Trauma Surgery and Orthopedics, 60590 Frankfurt am Main, Germany.ORCID 0000-0002-9728-4032
Rene D VerboketGoethe University Frankfurt, University Hospital, Department of Trauma Surgery and Orthopedics, 60590 Frankfurt am Main, Germany.
Ingo MarziGoethe University Frankfurt, University Hospital, Department of Trauma Surgery and Orthopedics, 60590 Frankfurt am Main, Germany.ORCID 0000-0003-3677-2910
Gernot HahneLysando Innovations Lab GmbH, 93053 Regensburg, Germany.
Volkhard A J KempfGoethe University Frankfurt, University Hospital, Institute of Medical Microbiology and Infection Control, 60596 Frankfurt am Main, Germany.ORCID 0000-0002-3321-7551
Stephan GöttigGoethe University Frankfurt, University Hospital, Institute of Medical Microbiology and Infection Control, 60596 Frankfurt am Main, Germany.ORCID 0000-0001-6896-5309

Funding

Federal Ministry of Education and Research 161B0769C
6 · The paper itself

Abstract

BACKGROUND/

objectivesInfections with antibiotic-resistant Gram-negative pathogens represent a major global threat to public health.

methodsAntibacterial activity of Art-Top3 was determined by broth microdilution, in vitro assays and in the

resultsHere, we report on a new Artilysin

conclusionOur findings collectively establish that Art-Top3 might be a candidate for novel therapeutic strategies of infections caused by multidrug-resistant

Indexed as

Acinetobacter baumanniiactivityantibacterial treatmentendolysinsresistance

Identifiers

PMID40001406
PMCPMC11851708

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.