Evidence map›Paper›PMID 40001358›Full record

ArticleAntibiotics (Basel, Switzerland)2025

Phage Therapy for Orthopaedic Infections: The First Three Cases from the United Kingdom.

Daniela I Munteanu, John Dunn, Gábor Apjok, Bálint Kintses, Johann Griselain, Griet Steurs, Christel Cochez, Sarah Djebara, Maya Merabishvili, Jean-Paul Pirnay and 8 more

Abstract read
In one paragraph

Article in Antibiotics (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Vancomycin and phage COP-80B combination therapy for Staphylococcus epidermidis periprosthetic joint infections: a preclinical mouse study.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026
    Article
  3. [Bacteriophage Therapy in Orthopaedics and Trauma].Acta chirurgiae orthopaedicae et traumatologiae Cechoslovaca · 2026
    Review
  4. Review
  5. Article
  6. Review
  7. Review
  8. Article
  9. Review
  10. Harnessing phages to tackle antimicrobial resistance: a Saudi Arabian perspective.Frontiers in cellular and infection microbiology · 2025
    Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Daniela I MunteanuDepartment of Medical Microbiology, Ninewells Hospital, Dundee DD1 9SY, UK.
John DunnPharmacy Department, Ninewells Hospital, Dundee DD1 9SY, UK.
Gábor ApjokSynthetic and Systems Biology Unit, Institute of Biochemistry, National Laboratory of Biotechnology, HUN-REN Biological Research Centre, Temesvári Krt. 62, 6726 Szeged, Hungary.ORCID 0000-0002-8627-2378
Bálint KintsesSynthetic and Systems Biology Unit, Institute of Biochemistry, National Laboratory of Biotechnology, HUN-REN Biological Research Centre, Temesvári Krt. 62, 6726 Szeged, Hungary.
Johann GriselainLaboratory of Molecular and Cellular Technology, Queen Astrid Military Hospital, Bruynstraat 1, 1120 Brussels, Belgium.
Griet SteursLaboratory of Molecular and Cellular Technology, Queen Astrid Military Hospital, Bruynstraat 1, 1120 Brussels, Belgium.
Christel CochezLaboratory of Molecular and Cellular Technology, Queen Astrid Military Hospital, Bruynstraat 1, 1120 Brussels, Belgium.
Sarah DjebaraCenter for Infectious Diseases ID4C, Queen Astrid Military Hospital, Bruynstraat 1, 1120 Brussels, Belgium.
Maya MerabishviliLaboratory of Molecular and Cellular Technology, Queen Astrid Military Hospital, Bruynstraat 1, 1120 Brussels, Belgium.ORCID 0000-0002-2566-0772
Jean-Paul PirnayLaboratory of Molecular and Cellular Technology, Queen Astrid Military Hospital, Bruynstraat 1, 1120 Brussels, Belgium.ORCID 0000-0002-6863-5219
Vida ŠtilecCOBIK, Mirce 21, 5270 Ajdovščina, Slovenia.
Matjaž PeterkaCOBIK, Mirce 21, 5270 Ajdovščina, Slovenia.ORCID 0000-0002-2798-1772
Emily A SimpsonDepartment of Medical Microbiology, Ninewells Hospital, Dundee DD1 9SY, UK.ORCID 0009-0008-4420-5952
Samantha DownieTrauma and Orthopaedic Department, Ninewells Hospital, Dundee DD1 9SY, UK.ORCID 0000-0002-3269-337X
Alasdair MacInnesTrauma and Orthopaedic Department, Ninewells Hospital, Dundee DD1 9SY, UK.ORCID 0000-0003-4960-1846
Graeme NicolTrauma and Orthopaedic Department, Ninewells Hospital, Dundee DD1 9SY, UK.
Benedict CliftTrauma and Orthopaedic Department, Ninewells Hospital, Dundee DD1 9SY, UK.
Joshua D JonesInfection Medicine, Edinburgh Medical School: Biomedical Sciences, University of Edinburgh, Chancellor's Building, 49 Little France Crescent, Edinburgh EH16 4SB, UK.ORCID 0000-0002-0981-1913

Funding

European Union's Horizon 2020 Research and Innovation Programme 739593National Laboratory of Biotechnology, Hungary 2022-2.1.1-NL-2022-00008Royal Higher Institute of Defence, Belgium HFM 24-17Slovenian Research Agency Grants no. L3-2620 and P3-0387Tayside Health Fund N/A
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

bacteriophagebone infectioncase seriesjoint infectionorthopaedicphage therapy

Identifiers

PMID40001358
PMCPMC11851713

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.