Evidence map›Paper›PMID 40001331›Full record

ArticleArchives of Iranian medicine2025

A Novel Candidate Gene

Niloofar Bazazzadegan, Mojgan Babanejad, Susan Banihashemi, Sanaz Arzhangi, Kimia Kahrizi, Kevin Ta Booth, Hossein Najmabadi

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Archives of Iranian medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Domain specific phenotypic expansion associated with variants inmedRxiv : the preprint server for health sciences · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Niloofar BazazzadeganGenetics Research Center, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran.ORCID 0000-0002-5455-272X
Mojgan BabanejadGenetics Research Center, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran.ORCID 0000-0003-2532-4303
Susan BanihashemiGenetics Research Center, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran.
Sanaz ArzhangiGenetics Research Center, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran.
Kimia KahriziGenetics Research Center, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran.ORCID 0000-0002-6587-7706
Kevin Ta BoothDepartment of Medical and Molecular Genetics, Indiana School of Medicine, Indianapolis, IN, USA.ORCID 0000-0003-3061-3652
Hossein NajmabadiGenetics Research Center, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran.ORCID 0000-0002-6084-7778

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cytoskeletal dynamics, the interplay of actin, microtubules, and septins, is a highly coordinated and tightly regulated process. Defects in the proteins involved can result in a wide range of cellular consequences. Hearing loss is the most common sensory defect and exhibits extraordinary genetic and phenotypic heterogeneity. Currently, there are more than 170 genes casually linked to non-syndromic hearing loss (NSHL), of which more than 60 are associated with autosomal dominant inheritance. Here, we add to this growing number by implicating

Indexed as

Hearing Loss, SensorineuralAdultExome SequencingFemaleGenes, DominantHumansIranMaleMutation, MissensePedigreeAutosomal dominant non-syndromic hearing lossIranMACF1Novel gene

Identifiers

PMID40001331
PMCPMC11862395

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.