Evidence map›Paper›PMID 40001288›Full record

ArticleMultiple sclerosis (Houndmills, Basingstoke, England)2025

Feasibility, reliability, and validity of ambulatory smartphone-administered cognitive tests in multiple sclerosis.

Josiah J Goga, Keara M Ginell, Yee To Ng, Dawn M Ehde, Kevin N Alschuler, Martin J Sliwinski, Nora E Fritz, Anna L Kratz

Abstract readValidation Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Multiple sclerosis (Houndmills, Basingstoke, England), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
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  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Josiah J GogaDepartment of Physical Medicine and Rehabilitation, University of Michigan, Ann Arbor, MI, USA.
Keara M GinellDepartment of Physical Medicine and Rehabilitation, University of Michigan, Ann Arbor, MI, USA.ORCID 0000-0001-6928-1080
Yee To NgDepartment of Physical Medicine and Rehabilitation, Survey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, MI, USA.
Dawn M EhdeDepartment of Rehabilitation Medicine, University of Washington, Seattle, WA, USA.ORCID 0000-0002-9555-2347
Kevin N AlschulerDepartment of Rehabilitation Medicine, Department of Neurology, University of Washington, Seattle, WA, USA.ORCID 0000-0003-2621-3461
Martin J SliwinskiCenter for Healthy Aging, Department of Human Development and Family Studies, Penn State University, University Park, PA, USA.
Nora E FritzDepartments of Health Care Sciences and Neurology, Wayne State University, Detroit, MI, USA.ORCID 0000-0002-4548-1077
Anna L KratzDepartment of Physical Medicine and Rehabilitation, University of Michigan, Ann Arbor, MI, USA.ORCID 0000-0002-3664-3898

Funding

Optimizing detection and prediction of changes in cognitive function in multiple sclerosis with novel ambulatory assessment methodsR01HD102337 · NICHD · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI FRITZ, NORA E., KRATZ, ANNA LOUISE · 2021 to 2025
$3.0M
NICHD NIH HHS R01 HD102337
6 · The paper itself

Abstract

backgroundDetection of subtle changes in cognition in multiple sclerosis (MS) may be enabled by ambulatory smartphone-based cognitive tests.

objectiveTo examine the feasibility, reliability, and validity of ambulatory cognitive tests in people with MS.

methodAdults with MS (

resultsParticipants completed 80.1% of available testing sessions. Reliability was 0.98 for dot memory and 0.99 for symbol search. Reliability attained ⩾0.90 within 3 days for dot memory and 1 day for symbol search. Symbol search scores correlated significantly with neuropsychological tests of processing speed (

conclusionSmartphone-administered tests of working memory and processing speed demonstrate good feasibility, reliability, and construct validity in MS.

Indexed as

Cognitive DysfunctionMultiple SclerosisNeuropsychological TestsSmartphoneAdultFeasibility StudiesFemaleHumansMaleMemory, Short-TermMiddle AgedReproducibility of Resultsecological momentary assessmentNeuropsychological testsprocessing speedworking memory

Identifiers

PMID40001288
PMCPMC11969573

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.