Evidence map›Paper›PMID 40001110›Full record

ReviewMolecular cancer2025

Traditional Chinese medicine in lung cancer treatment.

Zhichao Xi, Rongchen Dai, Yufei Ze, Xue Jiang, Mengfan Liu, Hongxi Xu

Abstract readReview
In one paragraph

Review in Molecular cancer, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 77 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
77citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

77 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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  11. "What really works for us?" exploring therapeutic strategies for non-small cell lung cancer: an umbrella review of systematic reviews and meta-analyses.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026
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17 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Zhichao Xi *School of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai, 201203, China.
Rongchen Dai *School of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai, 201203, China.
Yufei ZeSchool of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai, 201203, China.
Xue JiangSchool of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai, 201203, China.
Mengfan LiuSchool of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai, 201203, China. mengfanliush@163.com.
Hongxi XuSchool of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai, 201203, China. hxxu@shutcm.edu.cn.

Funding

National Natural Science Foundation of China 82404919National Postdoctoral Program for Innovative Talents BX20240230Postdoctoral Fellowship Program of China Postdoctoral Science Foundation GZC2023170Traditional Chinese Medicine Research Project of the Shanghai Municipal Health Commission 2024QN029
6 · The paper itself

Abstract

Lung cancer remains a major global health challenge and one of the leading causes of cancer-related deaths worldwide. Despite significant advancements in treatment, challenges such as drug resistance, side effects, metastasis and recurrence continue to impact patient outcomes and quality of life. In response, there is growing interest in complementary and integrative approaches to cancer care. Traditional Chinese medicine (TCM), with its long history, abundant clinical experience, holistic perspective and individualized approach, has garnered increasing attention for its role in lung cancer prevention and management. This review provides a comprehensive overview of the advances in TCM for lung cancer treatment, covering its theoretical foundation, treatment principles, clinical experiences and evidence supporting its efficacy. We also provide a systematic summary of the preclinical mechanisms, through which TCM impacts lung cancer, including the induction of cell death, reversal of drug resistance, inhibition of metastasis and modulation of immune responses. Additionally, future prospects for TCM in lung cancer treatment are discussed, offering insights into its expanded application and integration with modern medicine to address this challenging disease.

Indexed as

Drugs, Chinese HerbalLung NeoplasmsMedicine, Chinese TraditionalAnimalsDrug Resistance, NeoplasmHumansDrugs, Chinese HerbalCancer immunologyCancer metastasisChinese herbal medicineClinical trialsCombination therapyDrug resistanceLung cancerTraditional Chinese medicine

Identifiers

PMID40001110
PMCPMC11863959

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.