Evidence map›Paper›PMID 40001099›Full record

ArticleBMC ophthalmology2025

Correlation between contrast sensitivity and national eye institute visual function questionnaire (NEI VFQ-25) Rasch scores in patients with open-angle glaucoma: A cross-sectional study.

Rieko Nakano, Ryoko Igarashi, Tadamichi Akagi, Yuta Sakaue, Ryu Iikawa, Ayako Tazawa, Kinuko Kamada, Mao Arimatsu, Tetsuya Togano, Takeo Fukuchi

Abstract read
In one paragraph

Article in BMC ophthalmology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Rieko NakanoDivision of Ophthalmology and Visual Science, Graduate School of Medical and Dental Sciences, Niigata University, Niigata, Japan.
Ryoko IgarashiDivision of Ophthalmology and Visual Science, Graduate School of Medical and Dental Sciences, Niigata University, Niigata, Japan. iryoko@med.niigata-u.ac.jp.
Tadamichi AkagiDivision of Ophthalmology and Visual Science, Graduate School of Medical and Dental Sciences, Niigata University, Niigata, Japan.
Yuta SakaueDivision of Ophthalmology and Visual Science, Graduate School of Medical and Dental Sciences, Niigata University, Niigata, Japan.
Ryu IikawaDivision of Ophthalmology and Visual Science, Graduate School of Medical and Dental Sciences, Niigata University, Niigata, Japan.
Ayako TazawaDivision of Ophthalmology and Visual Science, Graduate School of Medical and Dental Sciences, Niigata University, Niigata, Japan.
Kinuko KamadaDivision of Ophthalmology and Visual Science, Graduate School of Medical and Dental Sciences, Niigata University, Niigata, Japan.
Mao ArimatsuDivision of Ophthalmology and Visual Science, Graduate School of Medical and Dental Sciences, Niigata University, Niigata, Japan.
Tetsuya ToganoDivision of Ophthalmology and Visual Science, Graduate School of Medical and Dental Sciences, Niigata University, Niigata, Japan.
Takeo FukuchiDivision of Ophthalmology and Visual Science, Graduate School of Medical and Dental Sciences, Niigata University, Niigata, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWe examined the relationship between contrast sensitivity (CS) and visual field stage/severity in patients with open-angle glaucoma (OAG), and correlated CS with Quality of Vision (QOV) scores.

methodsCS was measured under photopic (100 cd) and mesopic (10 cd) conditions in 218 eyes of 109 patients with OAG aged < 60 years. The glaucoma stages were divided into four groups according to the mean deviation (MD) of the Humphrey Field Analyzer (HFA) 24 - 2 or 10 - 2 Swedish Interactive Thresholding Algorithm (SITA) standard, and their relationship with CS was examined.

resultsThe results of the Japanese version of the National Eye Institute Visual Function Questionnaire-25 (NEI VFQ-25) in 79 patients were converted into Rasch scores and correlated with CS. Both HFA24-2 and 10 - 2 showed statistically significant improvements in all items except 10.2 cycles per degree (cpd) under mesopic conditions where CS decreased significantly (p < 0.05). Correlations between CS and NEI VFQ-25 Rasch scores were stronger in the worse eye (WE) at HFA24-2, 10 - 2, and foveal sensitivity thresholds. The measurement results strongly correlated under photopic conditions. Comparing the correlations at HFA24-2, 10 - 2, and foveal sensitivity thresholds, the correlation was strongest at the foveal sensitivity threshold.

conclusionsCS declines with progression in the visual field stage or severity. QOV score tends to decreases with a decline in CS.

Indexed as

Contrast SensitivityGlaucoma, Open-AngleSickness Impact ProfileVisual AcuityVisual FieldsAdultCross-Sectional StudiesFemaleHumansIntraocular PressureMaleMiddle AgedNational Eye Institute (U.S.)Quality of LifeSurveys and QuestionnairesVisual Field TestsContrast sensitivityGlaucomaQuality of visionRasch scores

Identifiers

PMID40001099
PMCPMC11863498

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.