Evidence map›Paper›PMID 40001094›Full record

ArticleBMC cancer2025

The feasibility and cost-effectiveness of implementing mobile low-dose computed tomography with an AI-based diagnostic system in underserved populations.

Feifei Huang, Xiujing Lin, Yuezhen Hong, Yue Li, Yonglin Li, Wei-Ti Chen, Weisheng Chen

Abstract read
In one paragraph

Article in BMC cancer, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 4 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Feifei Huang *School of Nursing, Fujian Medical University, Fuzhou, 350122, Fujian, China.
Xiujing Lin *School of Nursing, Fujian Medical University, Fuzhou, 350122, Fujian, China.
Yuezhen HongSchool of Nursing, Fujian Medical University, Fuzhou, 350122, Fujian, China.
Yue LiSchool of Basic Medicine, Fujian Medical University, Fuzhou, 350122, Fujian, China.
Yonglin LiSchool of Nursing, Fujian Medical University, Fuzhou, 350122, Fujian, China.
Wei-Ti ChenSchool of Nursing, University of California Los Angeles, Los Angeles, CA, USA.
Weisheng ChenDepartment of Thoracic oncology surgery, Clinical Oncology School of Fujian Medical University, Fujian Cancer Hospital, No 420 Fuma Road, Jin 'an District, Fuzhou City, Fujian Province, China. 723471312@qq.com.

Funding

General Project of Fujian Provincial Nature Science Foundation 2021J01435the National Natural Science Foundation of China 72304068
6 · The paper itself

Abstract

backgroundLow-dose computed tomography (LDCT) significantly increases early detection rates of lung cancer and reduces lung cancer-related mortality by 20%. However, many significant screening barriers remain. This study conduct an initial feasibility and cost-effectiveness analysis of a community-based program that used a mobile low-dose computed tomography (LDCT) scan unit and discuss the operational challenges faced during its implementation.

methodsThis study was conducted in rural areas in Fujian Province, China from July 2022 to August 2022. Individuals aged 40 years and above who had not previously undergone LDCT and who were socioeconomically marginalized were included. Participants received a LDCT program from a multidisciplinary research team. Physicians analyzed the images with the assistance of artificial intelligence "InferRead CT Lung Research" and completed structured reports on their impressions. The primary evaluation indicators for mobile LDCT screening effectiveness were the lung cancer detection rate and diagnosis rate, while the main evaluation indicators for cost-effective analysis were the cost-effective ratio and early detection cost index.

resultsA total of 10,159 individuals participated in this study. The detection rates of suspected lung cancer cases and confirmed cases were 1.06% (n = 108) and 0.7% (n = 71), respectively. The cost of lung cancer screening (LCS) was ¥1,203,504 (US$188,847.71), the average cost per screening was ¥118.47 (US$18.65), and the cost effective ratios for the detection of suspected lung cancer and confirmed lung cancer were ¥11,143.56 (US$1,753.29) and ¥16,950.76 (US$2,669.94), respectively. The early detection cost indices for suspected lung cancer were 0.09 and 0.13 for confirmed lung cancer, respectively.

conclusionThis LDCT with artificial intelligence model for LCS holds economic promise for reducing health disparities in underserved areas and promote larger populations in similar low-income country.

Indexed as

Artificial IntelligenceEarly Detection of CancerLung NeoplasmsTomography, X-Ray ComputedAdultAgedChinaCost-Benefit AnalysisFeasibility StudiesFemaleHumansMaleMiddle AgedRadiation DosageVulnerable PopulationsArtificial intelligenceChinaEarly detection of cancerHigh-risk populationLung cancer

Identifiers

PMID40001094
PMCPMC11863806

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.