SynthesisJournal of orthopaedic surgery and research2025
Effect of vertebral kyphoplasty versus vertebroplasty on pain and indicators of imaging parameters of the injured vertebrae in patients with osteoporotic vertebral compression fractures: a meta-analysis.
Synthesis in Journal of orthopaedic surgery and research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
6 citing papers in PubMed.
- Percutaneous vertebroplasty and percutaneous kyphoplasty for osteoporotic vertebral compression fractures: medium- and long-term evaluation of clinical outcomes and affecting factors.BMC musculoskeletal disorders · 2026Article
- Intraoperative Suction-Assisted Kyphoplasty for Immediate Removal of Posterior PMMA Extravasation in Decompressed Vertebral Compression Fractures.Journal of clinical medicine · 2026Article
- Article
- Influence of thoracolumbar kyphotic Cobb angle on prognosis after PKP surgery.Scientific reports · 2025Article
- Genant grade-based stratification in percutaneous curved kyphoplasty: Superior early analgesic efficacy and cement distribution characteristics in moderate to severe osteoporotic vertebral compression fractures.Neurosurgical review · 2025Article
- The risk factors of osteoporotic vertebral compression fracture accompanied with thoracolumbar fascial injury: a single-center retrospective study.Scientific reports · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo systematically evaluate the effects of vertebroplasty (VP) and kyphoplasty (KP) on pain and spinal imaging parameters in patients with osteoporotic vertebral compression fractures (OVCF).
methodsA comprehensive search of eight databases was conducted from inception to November 2024 to identify randomised controlled trials (RCTs) published in Chinese and English. Eligible studies included clinical RCTs comparing KP and VP in patients with OVCF, assessing vertebral pain and imaging parameters. Risk of bias and methodological quality were assessed using the Cochrane Appraisal Tool. Combined effects were calculated using a random effects model. Heterogeneity was assessed using the I
resultsA total of 16 randomised controlled trials involving 1738 patients were included. The analysis revealed no statistically significant difference between KP and VP in pain reduction (SMD = 0.08, 95% CI = -0.04 to 0.20, P = 0. 19) or spinal function (SMD = 0.04, 95% CI = -0.11 to -0.19, P = 0. 62). However, KP demonstrated significantly better outcomes than VP in vertebral compression rate (SMD = 1.39, 95% CI = 0.81 to 1.96, P < 0. 00001), Cobb angle (SMD = 1.83, 95% CI = 0.99 to 2.68, P < 0. 0001) and the incidence of cement leakage (OR = 1.92, 95% CI = 1.41 to 2.62, P < 0. 0001).
conclusionOur results suggest that KP is more effective than VP in improving postoperative vertebral compression rate and Cobb angle, and reducing the incidence of cement leakage.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.