Evidence map›Paper›PMID 40001026›Full record

ArticleBMC genomics2025

Physiological and transcriptomic evidence revealed the role of exogenous GABA in enhancing salt tolerance in strawberry seedlings.

Yunting Zhang, Meiyi Deng, Bangyu Lin, Su Tian, Yan Chen, Shan Huang, Yuanxiu Lin, Mengyao Li, Wen He, Yan Wang and 6 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC genomics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Salinity Stress in Strawberry (Plants (Basel, Switzerland) · 2026
    Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Yunting Zhang *College of Horticulture, Sichuan Agricultural University, Chengdu, 611130, China.
Meiyi Deng *College of Horticulture, Sichuan Agricultural University, Chengdu, 611130, China.
Bangyu Lin *College of Horticulture, Sichuan Agricultural University, Chengdu, 611130, China.
Su TianCollege of Horticulture, Sichuan Agricultural University, Chengdu, 611130, China.
Yan ChenCollege of Horticulture, Sichuan Agricultural University, Chengdu, 611130, China.
Shan HuangCollege of Horticulture, Sichuan Agricultural University, Chengdu, 611130, China.
Yuanxiu LinCollege of Horticulture, Sichuan Agricultural University, Chengdu, 611130, China.
Mengyao LiCollege of Horticulture, Sichuan Agricultural University, Chengdu, 611130, China.
Wen HeCollege of Horticulture, Sichuan Agricultural University, Chengdu, 611130, China.
Yan WangCollege of Horticulture, Sichuan Agricultural University, Chengdu, 611130, China.
Yong ZhangCollege of Horticulture, Sichuan Agricultural University, Chengdu, 611130, China.
Qing ChenCollege of Horticulture, Sichuan Agricultural University, Chengdu, 611130, China.
Ya LuoCollege of Horticulture, Sichuan Agricultural University, Chengdu, 611130, China.
Xiaorong WangCollege of Horticulture, Sichuan Agricultural University, Chengdu, 611130, China.
Xianjie GuMianyang Academy of Agricultural Sciences, Mianyang, 621000, China. heyggu@gmail.com.
Haoru TangCollege of Horticulture, Sichuan Agricultural University, Chengdu, 611130, China. htang@sicau.edu.cn.

Funding

Double Support Project of Discipline Construction of Sichuan Agricultural University 03573134National Natural Science Foundation of China 32302479Natural Science Foundation of Sichuan Province 2023NSFSC1243
6 · The paper itself

Abstract

As one of the most salt-sensitive crops, strawberry production is severely limited by salt stress. γ--aminobutyric acid (GABA) has been reported to play an important role in the immune response of plants. In this study, the physiological and transcriptomic changes in strawberry seedlings treated with GABA under salt stress were investigated to explore the effect of GABA on salt tolerance. The results showed that exogenous GABA maintained high osmolyte levels, increased antioxidant capacity, and decreased the ROS levels in strawberry leaves under salt stress; the MDA was reduced by 3.27-31.46%, with 10 mM being the most significant effect; the total (Spd + Spm)/ Put ratio was upregulated after GABA treatments. More strikingly, the plants treated with 10 mM GABA significantly increased chlorophyll content and net photosynthetic rate in salt-stressed plants, which was explained by the transcriptomic data showing that the expression levels of most of chlorophyll metabolism and photosynthesis-related genes were upregulated. Furthermore, 38 potential TFs belonging to the WRKY, AP2/ERF, and MYB families were identified that may be positively involved in GABA-induced salt tolerance. Co-expressed network analysis revealed that some of these TFs, such as RAP2.7, WRKY46, and MYB306, were significantly positively correlated with chlorophyll metabolism. These findings provide an important basis for the use of GABA in the breeding of strawberry resistant to salt stress.

Indexed as

Fragariagamma-Aminobutyric AcidSalt ToleranceSeedlingsTranscriptomeChlorophyllGene Expression ProfilingGene Expression Regulation, PlantPhotosynthesisPlant LeavesPlant ProteinsChlorophyllgamma-Aminobutyric AcidPlant ProteinsAntioxidant capacityChlorophyll metabolismGABASalt toleranceStrawberry

Identifiers

PMID40001026
PMCPMC11863477

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.