Evidence map›Paper›PMID 40001014›Full record

Observational studyBMC psychiatry2025

Implementation of the healthy heart tool- an algorithm with potential cardiometabolic health benefits in persons with severe mental illness.

Elisabeth Haug Lund-Stenvold, Petter A Ringen, Ole A Andreassen, Torfinn L Gaarden, Cecilie B Hartberg, Erik Johnsen, Silje Myklatun, Kåre Osnes, Kjetil Sørensen, Arne Vaaler and 3 more

Registry-linked trialAbstract readMulticenter StudyObservational Study
In one paragraph

Observational study in BMC psychiatry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06807242 (Observational Study with Historic Control Cohort of the Implementation of a Tool for Reduction of Cardiovascular Risk in Patients with Severe Mental Disorders), which is not on this map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06807242 completednot on this map

Observational Study with Historic Control Cohort of the Implementation of a Tool for Reduction of Cardiovascular Risk in Patients with Severe Mental Disorders

TypeobservationalSponsorOslo University HospitalRan2017 to 2019Enrolled270ConditionsSchizophrenic Psychoses, Schizophrenia, Severe Mental Disorder
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Elisabeth Haug Lund-StenvoldDepartment of Clinical Medicine, UiT The Arctic University of Norway, Tromsø, Norway. elisabeth.h.lund@uit.no.
Petter A RingenDivision of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway.
Ole A AndreassenInstitute of Clinical Medicine, University of Oslo, Oslo, Norway.
Torfinn L GaardenDivision of Mental Health and Substance Abuse, Diakonhjemmet Hospital, Oslo, Norway.
Cecilie B HartbergDivision of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway.
Erik JohnsenDivision of Mental Health and Addiction, NORMENT Centre of Excellence, Oslo University Hospital, Oslo, Norway.
Silje MyklatunDivision of Mental Health and Substance Abuse, Diakonhjemmet Hospital, Oslo, Norway.
Kåre OsnesDivision of Mental Health and Substance Abuse, Diakonhjemmet Hospital, Oslo, Norway.
Kjetil SørensenDivision of Mental Health, St Olav's University Hospital, Østmarka, Trondheim, Norway.
Arne VaalerDepartment of Acute Psychiatry, St. Olav's University Hospital, Trondheim, Norway.
Serena TonstadSection for Preventive Cardiology Endocrinology, Morbid Obesity and Preventive Medicine, Oslo University Hospital, Oslo, Norway.
John A EnghDivision of Mental Health and Addiction, Vestfold Hospital Trust, Tønsberg, Norway.
Anne HøyeDepartment of Clinical Medicine, UiT The Arctic University of Norway, Tromsø, Norway.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCardiometabolic diseases are the main causes of death in persons with severe mental illness (SMI), highlighting the need to improve management of cardiovascular risk factors in both primary and specialized health care. The "Healthy Heart Tool" aims at helping health care workers to identify persons at risk, and to initiate proper interventions. Here we investigate if the recommendations in the Healthy Heart Tool are followed one year after implementation and whether implementation of the tool improved cardiometabolic risk factors in SMI.

methodsData from 270 individuals with SMI from six Norwegian hospitals were collected at baseline and at 12 months after implementation of the Healthy Heart Tool throughout the health care services. Changes from baseline to 12 months follow-up were analyzed using chi-square and independent t-tests, whereas implementation effects were analyzed using logistic general linear mixed models.

resultsAfter implementing the Healthy Heart Tool, significantly more persons received dietary advice and/or salt restriction advice (75.5% vs. 84.8%, p = 0.035). After controlling for Body Mass Index (BMI) ≥ 30 and sex, there was an odds ratio (OR) of 8.9 (95% CI 1.42-55.77) for receiving dietary advice and/or advice on salt reduction. There was a significant reduction (p = 0.016) in numbers of participants with high levels of total serum cholesterol ≥ 5 mmol/ (54.4% vs. 46.3%).

conclusionsImplementing the Healthy Heart Tool can increase awareness of cardiovascular risk factors in patients with SMI. The intervention increased the proportion of individuals who received dietary and salt reduction advice and decreased the proportion of individuals with high cholesterol levels. However, due to the small numbers, these results should be interpreted with caution. Nonetheless, the findings suggest that the Healthy Heart Tool may be an effective means for improving the management of cardiovascular risk factors in individuals with SMI in typical clinical settings. TRIAL REGISTRATIONS: The trial was retrospectively registered in ClinicalTrials.gov 29.01.25, ID NCT06807242.

Indexed as

AlgorithmsCardiovascular DiseasesMental DisordersAdultCardiometabolic Risk FactorsFemaleHumansMaleMiddle AgedNorwayCardiovascular riskMortality risk reductionSevere mental illness

Identifiers

PMID40001014
PMCPMC11863842

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.