Evidence map›Paper›PMID 40000692›Full record

ArticleScientific reports2025

Objectively measured moderate-to-vigorous physical activity does not attenuate prospective weight gain among african-origin adults spanning the epidemiological transition.

Jessica C Davies, Candice Choo-Kang, Larske Soepnel, Hayli Geffen, Chad Africa, Asanda Mtintsilana, Pascal Bovet, Bharathi Viswanathan, Kweku Bedu-Addo, Jacob Plange-Rhule and 14 more

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

24 authors.

Jessica C DaviesDivision of Epidemiology and Biostatistics, School of Public Health, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa. jess.davies@uct.ac.za.
Candice Choo-KangPublic Health Sciences, Parkinson School of Health Sciences and Public Health, Loyola University Chicago, Maywood, IL, USA.
Larske SoepnelDivision of Epidemiology and Biostatistics, School of Public Health, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.
Hayli GeffenDivision of Epidemiology and Biostatistics, School of Public Health, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.
Chad AfricaDivision of Epidemiology and Biostatistics, School of Public Health, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.
Asanda MtintsilanaDivision of Epidemiology and Biostatistics, School of Public Health, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.
Pascal BovetUniversity Center for Primary Care and Public Health (Unisanté), Lausanne, Switzerland.
Bharathi ViswanathanMinistry of Health, Victoria, Republic of Seychelles.
Kweku Bedu-AddoDepartment of Physiology, School of Medical Sciences, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.
Jacob Plange-RhuleDepartment of Physiology, School of Medical Sciences, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.
Prince Oti BoatengDepartment of Physiology, School of Medical Sciences, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.
Kingsley ApusigaDepartment of Physiology, School of Medical Sciences, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.
Oscar Akunor DeiDepartment of Physiology, School of Medical Sciences, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.
Terrence E ForresterSolutions for Developing Countries, University of the West Indies, Mona, Kingston, Jamaica.
Marie WilliamsSolutions for Developing Countries, University of the West Indies, Mona, Kingston, Jamaica.
Estelle V LambertResearch Centre for Health through Physical Activity, Lifestyle and Sport (HPALS), Department of Human Biology, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.
Dale E RaeResearch Centre for Health through Physical Activity, Lifestyle and Sport (HPALS), Department of Human Biology, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.
Nandipha SinyanyaResearch Centre for Health through Physical Activity, Lifestyle and Sport (HPALS), Department of Human Biology, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.
Brian T LaydenDepartment of Medicine, University of Illinois at Chicago, Chicago, IL, USA.
Jack A GilbertDepartment of Pediatrics, Center for Microbiome Innovation, University of California San Diego, La Jolla, San Diego, CA, USA.
Gertrude Ecklu-MensahDepartment of Pediatrics, Center for Microbiome Innovation, University of California San Diego, La Jolla, San Diego, CA, USA.
Cara JoycePublic Health Sciences, Parkinson School of Health Sciences and Public Health, Loyola University Chicago, Maywood, IL, USA.
Amy LukePublic Health Sciences, Parkinson School of Health Sciences and Public Health, Loyola University Chicago, Maywood, IL, USA.
Lara R DugasDivision of Epidemiology and Biostatistics, School of Public Health, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.

Funding

METS-Sleep: Sleep timing, gut microbiota and cardiometabolic risk across the Epidemiologic TransitionR01HL148271 · NHLBI · LOYOLA UNIVERSITY CHICAGO · PI DUGAS, LARA RUTH, LAYDEN, BRIAN THOMAS · 2019 to 2023
$3.5M
Gut microbiota, short chain fatty acids, and adiposity across the epidemiologic transitionR01DK111848 · NIDDK · LOYOLA UNIVERSITY CHICAGO · PI DUGAS, LARA RUTH · 2017 to 2021
$3.0M
Modeling the epidemiologic transition: Energy expenditure, obesity and diabetesR01DK080763 · NIDDK · LOYOLA UNIVERSITY CHICAGO · PI LUKE, AMY H · 2009 to 2012
$2.4M
NHLBI NIH HHS R01 HL148271NIDDK NIH HHS R01 DK080763NIDDK NIH HHS R01 DK111848NIH HHS 1R01DK80763, R01DK111848, R01HL148271
6 · The paper itself

Abstract

Traditional obesity-related public health messaging often includes physical activity (PA) recommendations. However, at the population level, the data are conflicting, especially when comparing different self-reported vs. measured techniques across different settings and populations. We measured the association between moderate-to-vigorous intensity PA (MVPA) and prospective weight change across five African-origin populations and the extent to which MVPA attenuated weight change over time. At baseline, 2,500 adults (median age: 37y) were recruited into the Modelling the Epidemiologic Transition Study (METS), from Ghana, South Africa, Jamaica, Seychelles, and US. 2000 participants were followed up 8 years later, with 851 participants having complete 7-day accelerometry to measure MVPA at both time points. Generalised estimating equations were used to explore the longitudinal association between weight and MVPA adjusted for several confounders. The obesity prevalence at baseline was 27.5% which increased to 38.0% at follow-up. Baseline MVPA varied from 7 (IQR: 4, 16) min/day in US women to 52 (IQR: 36, 78) min/day in South African men, and similarly at follow-up ranged from 8 min/day to 41 min/day among the same participant groups. While overall, engaging in higher MVPA levels was associated with a lower body weight, such that every additional 30 min of MVPA equalled a 600 g lower body weight (p = 0.04), the interaction between time and MVPA was not statistically significant (p = 0.18). Therefore, regardless of the amount of MVPA at any time point, body weight increased over time. Despite the association between MVPA and weight, our results suggest that objectively measured longitudinal MVPA was not associated with the change in 8-year weight in African-origin adults. Our research confirms that while PA is a critical determinant of cardiovascular health, it alone may not be enough to stem the rising obesity burden.

Indexed as

ExerciseObesityWeight GainAccelerometryAdultBlack PeopleFemaleGhanaHumansJamaicaMaleMiddle AgedProspective StudiesSeychellesSouth AfricaUnited StatesObesityObjectively measured physical activityProspective weight change

Identifiers

PMID40000692
PMCPMC11862232

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LicenceCC BY-NC-ND
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.