Evidence map›Paper›PMID 40000686›Full record

ArticleScientific reports2025

Comprehensive analysis of Metacrinus rotundus full length transcriptome.

Zhong Li, Yue Dong, Xuebao He, Chen Han, Xiaomei Liao, Jing Mo, Qian Zhang, Xuelei Zhang, Zongling Wang, Qinzeng Xu

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Zhong LiCollege of Environmental Science and Engineering, Ocean University of China, Qingdao, 266100, China.
Yue DongCollege of Environmental Science and Engineering, Ocean University of China, Qingdao, 266100, China.
Xuebao HeLaboratory of Marine Biodiversity, Third Institute of Oceanography, MNR, Xiamen, 361005, China.
Chen HanKey Laboratory of Marine Eco-Environmental Science and Technology, First Institute of Oceanography, MNR, Qingdao, 266061, China.
Xiaomei LiaoKey Laboratory of Marine Eco-Environmental Science and Technology, First Institute of Oceanography, MNR, Qingdao, 266061, China.
Jing MoKey Laboratory of Marine Eco-Environmental Science and Technology, First Institute of Oceanography, MNR, Qingdao, 266061, China.
Qian ZhangKey Laboratory of Marine Eco-Environmental Science and Technology, First Institute of Oceanography, MNR, Qingdao, 266061, China.
Xuelei ZhangKey Laboratory of Marine Eco-Environmental Science and Technology, First Institute of Oceanography, MNR, Qingdao, 266061, China.
Zongling WangKey Laboratory of Marine Eco-Environmental Science and Technology, First Institute of Oceanography, MNR, Qingdao, 266061, China.
Qinzeng XuKey Laboratory of Marine Eco-Environmental Science and Technology, First Institute of Oceanography, MNR, Qingdao, 266061, China. xqz08@163.com.

Funding

National Natural Science Foundation of China 42176135
6 · The paper itself

Abstract

Modern stalked crinoids, an important group of echinoderms, represent the ancestral mode of crinoids, and studying their evolution is key to understanding the evolution of echinoderms. In this study, we selected Metacrinus rotundus, a species of modern stalked crinoids, for investigation. We generated M. rotundus transcripts using Pacific Biosciences single-molecule real-time (SMRT) long-read sequencing technology. A total of 160,849 full-length (FL) transcripts were captured by Iso-Seq, with a mean length of 2,470 bp. Of these FL transcripts, 110,859 were well-annotated based on public database. A portion of transcripts remained unannotated, representing potential novel genes for M. rotundus. Additionally, we identified 71,740 long-noncoding RNA (LncRNAs), 57,548 simple sequence repeats (SSRs), and 3,486 hypothetical transcript factors (TFs). By comparing Holothuroid and Echinoid, M. rotundus have a higher proportion of zf-CCCH and TF_Otx within TFs, as well as trinucleotide SSRs within SSRs. Notably, transposable elements (TEs) make up a large proportion of the full-length transcriptome of M. rotundus, with RNA transposons being the largest class of annotated TEs. Our study enhances understanding of the characteristics of M. rotundus transcriptome and provides a valuable genetic resource for further studies on adaptive evolution in this species, as well as in other crinoids.

Indexed as

EchinodermataTranscriptomeAnimalsGene Expression ProfilingMicrosatellite RepeatsMolecular Sequence AnnotationRNA, Long NoncodingRNA, Long NoncodingSingle-molecule real-timeStalked crinoidTransposable elements

Identifiers

PMID40000686
PMCPMC11861897

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.