Evidence map›Paper›PMID 40000634›Full record

ArticleNPJ science of food2025

Cultivation of bovine lipid chunks on Aloe vera scaffolds.

Gilad Gome, Benyamin Chak, Shadi Tawil, Itai Rotem, Ivana Ribarski-Chorev, Jonathan Giron, Oded Shoseyov, Sharon Schlesinger

Abstract read
In one paragraph

Article in NPJ science of food, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Starch-Based Scaffolds for Cultivated Meat Production: Challenges and Perspectives.Comprehensive reviews in food science and food safety · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Gilad GomeDepartment of Plant Sciences, The Robert H. Smith Faculty of Agriculture, Food and Environment, The Hebrew University of Jerusalem, Rehovot, Israel. giladgome@mail.huji.ac.il.
Benyamin ChakDepartment of Animal Sciences, The Robert H. Smith Faculty of Agriculture, Food and Environment, The Hebrew University of Jerusalem, Rehovot, Israel.
Shadi TawilDepartment of Animal Sciences, The Robert H. Smith Faculty of Agriculture, Food and Environment, The Hebrew University of Jerusalem, Rehovot, Israel.ORCID http://orcid.org/0009-0000-7989-6580
Itai RotemDepartment of Animal Sciences, The Robert H. Smith Faculty of Agriculture, Food and Environment, The Hebrew University of Jerusalem, Rehovot, Israel.
Ivana Ribarski-ChorevDepartment of Animal Sciences, The Robert H. Smith Faculty of Agriculture, Food and Environment, The Hebrew University of Jerusalem, Rehovot, Israel.
Jonathan GironSammy Ofer School of Communication, Reichman University, Herzliya, Israel.
Oded ShoseyovDepartment of Plant Sciences, The Robert H. Smith Faculty of Agriculture, Food and Environment, The Hebrew University of Jerusalem, Rehovot, Israel.
Sharon SchlesingerDepartment of Animal Sciences, The Robert H. Smith Faculty of Agriculture, Food and Environment, The Hebrew University of Jerusalem, Rehovot, Israel. sharon.shle@mail.huji.ac.il.ORCID http://orcid.org/0000-0001-9549-2383

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aloe vera, renowned for its medicinal and food applications, offers a sustainable, scalable, and cost-effective scaffold material for cultured meat production. Our method repurposes Aloe vera parenchyma into a sustainable and innovative scaffold for CM production. These scaffolds, derived from agricultural byproducts, feature a porous structure that retains liquids and supports bovine mesenchymal stem cell (bMSC) adhesion, proliferation, and extracellular matrix formation. By incorporating oleic acid, the scaffolds enable the accumulation of fat-like tissue, creating "lipid chunks" that can enhance the texture and flavor profile of plant-based meat alternatives. Furthermore, scalability is addressed by culturing the scaffolds in a macrofluidic single-use bioreactor (MSUB), showcasing the potential for large-scale production. This work demonstrates Aloe vera scaffold's versatility as a cost-effective material and highlights its promise for sustainable protein solutions and tissue engineering applications.

Identifiers

PMID40000634
PMCPMC11862248

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.