Evidence map›Paper›PMID 40000624›Full record

ArticleNature communications2025

A column-like organization for ocular dominance in mouse visual cortex.

Pieter M Goltstein, David Laubender, Tobias Bonhoeffer, Mark Hübener

Abstract read
In one paragraph

Article in Nature communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Binocular Circuitry as a Model for Understanding Experience-Dependent Circuit Development across the Mammalian Cortex.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026
    Review
  4. Article
  5. Review
  6. Development of the Binocular Circuit.Annual review of neuroscience · 2024
    Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Pieter M GoltsteinMax Planck Institute for Biological Intelligence, Martinsried, Germany. pieter.goltstein@bi.mpg.de.ORCID http://orcid.org/0000-0001-8895-0841
David LaubenderMax Planck Institute for Biological Intelligence, Martinsried, Germany.ORCID http://orcid.org/0009-0005-8424-1657
Tobias BonhoefferMax Planck Institute for Biological Intelligence, Martinsried, Germany.ORCID http://orcid.org/0000-0001-7897-6634
Mark HübenerMax Planck Institute for Biological Intelligence, Martinsried, Germany. mark.huebener@bi.mpg.de.ORCID http://orcid.org/0000-0001-8367-9132

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The columnar organization of response properties is a fundamental feature of the mammalian visual cortex. However, columns have not been observed universally across all mammalian species. Here, we report the discovery of clusters of ipsilateral eye preferring neurons in layer 4 of the mouse primary visual cortex. These clusters extend into layer 2/3 and upper layer 5, forming a column-like pattern for ocular dominance. Our observation of such structures in this minute cortical area sets a new boundary condition for models explaining the emergence of functional organizations in the neocortex.

Indexed as

Dominance, OcularNeuronsPrimary Visual CortexVisual CortexAnimalsMaleMiceMice, Inbred C57BLPhotic Stimulation

Identifiers

PMID40000624
PMCPMC11861588

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.