Evidence map›Paper›PMID 40000552›Full record

ArticleProbiotics and antimicrobial proteins2025

Postbiotics from Saccharomyces cerevisiae RC016 Cell Wall (Formerly Classified as a Prebiotic): Exploring In Vitro and In Vivo Benefits.

Valeria L Poloni, María Eugenia Pérez, Franco Escobar, Julieta Luna, Yanina Pereyra, Andrea Cristofolini, Alejandra Magnoli, Lilia Cavaglieri

Abstract read
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In one paragraph

Article in Probiotics and antimicrobial proteins, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Valeria L PoloniDepartamento de Microbiología E Inmunología, Universidad Nacional de Río Cuarto, Ruta 36 Km 601, (5800), Río Cuarto, Cordoba, Argentina. vpoloni@exa.unrc.edu.ar.
María Eugenia PérezDepartamento de Microbiología E Inmunología, Universidad Nacional de Río Cuarto, Ruta 36 Km 601, (5800), Río Cuarto, Cordoba, Argentina.
Franco EscobarDepartamento de Microbiología E Inmunología, Universidad Nacional de Río Cuarto, Ruta 36 Km 601, (5800), Río Cuarto, Cordoba, Argentina.
Julieta LunaDepartamento de Producción Animal, Facultad de Agronomía y Veterinaria, Universidad Nacional de Río Cuarto, Ruta 36 Km 601, (5800), Río Cuarto, Cordoba, Argentina.
Yanina PereyraDepartamento de Tecnología Química, Facultad de Ingeniería (IITEMA), Universidad Nacional de Río Cuarto, Ruta 36 Km 601, (5800), Cordoba, Argentina.
Andrea CristofoliniDepartamento de Microscopía Electrónica, Universidad Nacional de Río Cuarto, Ruta 36 Km 601, (5800), Río Cuarto, Cordoba, Argentina.
Alejandra MagnoliDepartamento de Producción Animal, Facultad de Agronomía y Veterinaria, Universidad Nacional de Río Cuarto, Ruta 36 Km 601, (5800), Río Cuarto, Cordoba, Argentina.
Lilia CavaglieriDepartamento de Microbiología E Inmunología, Universidad Nacional de Río Cuarto, Ruta 36 Km 601, (5800), Río Cuarto, Cordoba, Argentina.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The objective of this work was to obtain postbiotics derived from the cell wall of Saccharomyces cerevisiae RC016 by applying different strategies and to characterize them in terms of their antitoxin capacity in vitro and their in vivo impact on intestinal integrity, evaluating the modulation of the microbiota and the histomorphometry of the intestine. Moreover, the impact of dried strategies on chemical groups related to food toxin adsorption was analyzed. Nine mechanical and enzymatic cell disruption treatments were assayed using S. cerevisiae RC016 biomass to obtain the postbiotic under study. Then, postbiotics were characterized using high-resolution optical microscopy and assayed for in vitro studies related to their antitoxin activity (adsorption and degradation of aflatoxin B

Indexed as

Cell WallPrebioticsSaccharomyces cerevisiaeAnimalsFemaleGastrointestinal MicrobiomeIntestinesMaleMiceMice, Inbred BALB CPrebioticsCell wallPostbioticPrebioticSaccharomyces cerevisiae

Identifiers

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.