ArticleSurgical endoscopy2025
Impact of surgical timing on postoperative quality of life in acute cholecystitis: a comparative analysis of early, intermediate, and delayed laparoscopic cholecystectomy.
Article in Surgical endoscopy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Association of Serum CX3CL1 and TSLP Expression with Postoperative Pain Severity in Patients Undergoing Laparoscopic Cholecystectomy: A Prospective Study.Journal of pain research · 2026Article
- Ultrasound-guided percutaneous transhepatic cholecystic puncture and drainage for acute severe cholecystitis-a Case Report.Frontiers in medicine · 2025Article
Corrections and comments
- Erratum issued
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAcute cholecystitis, primarily caused by gallstones, is a serious condition that may lead to severe complications. The optimal timing of surgery for acute cholecystitis is still under debate. Early cholecystectomy is generally preferred to prevent complications and improve postoperative outcomes. This study aimed to evaluate the impact of early, intermediate, and delayed laparoscopic cholecystectomy on postoperative quality of life (QoL) in patients with acute cholecystitis.
methodsThis retrospective study included 201 patients who underwent laparoscopic cholecystectomy for acute cholecystitis between May 2019 and February 2023. Patients were categorized into three groups based on the timing of surgery: early (within one week), intermediate (1-6 weeks), and delayed (after six weeks). The Gastrointestinal Quality of Life Index (GIQLI) was used to evaluate QoL six months postoperatively. Data on patient demographics, surgery timing, and cholecystitis severity (based on the Tokyo Guidelines) were analyzed using univariate and multivariate regression models.
resultsThe mean age of patients was 56.0 ± 14.9 years, and 65.7% were female. Early cholecystectomy was performed in 30.8% of cases, intermediate in 16.9%, and delayed in 52.2%. The median GIQLI score was 116. Patients who underwent early surgery had significantly higher GIQLI scores compared to those in the intermediate group (p < 0.001). No significant difference was observed between early and delayed surgery (p = 0.199). Multivariate analysis showed that intermediate surgery negatively affected QoL (p < 0.001), while cholecystitis severity was also a significant factor (p = 0.006).
conclusionsEarly laparoscopic cholecystectomy significantly improves postoperative QoL compared to intermediate surgery. Delayed surgery provides similar QoL outcomes to early surgery. However, intermediate cholecystectomy may lead to poorer QoL due to heightened surgical complexity and increased complications. Early intervention should be prioritized to optimize patient outcomes.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.