Evidence map›Paper›PMID 40000419›Full record

ArticleRNA biology2025

Defining the methanogenic SECIS element

Nils Peiter, Anna Einert, Pauline Just, Frida Jannasch, Marija Najdovska, Michael Rother

Abstract read
In one paragraph

Article in RNA biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Nils PeiterFakultät Biologie, Technische Universität Dresden, Dresden, Germany.ORCID 0000-0002-0181-6605
Anna EinertFakultät Biologie, Technische Universität Dresden, Dresden, Germany.
Pauline JustFakultät Biologie, Technische Universität Dresden, Dresden, Germany.ORCID 0009-0009-8421-1545
Frida JannaschFakultät Biologie, Technische Universität Dresden, Dresden, Germany.ORCID 0009-0000-7185-436X
Marija NajdovskaFakultät Biologie, Technische Universität Dresden, Dresden, Germany.ORCID 0009-0005-7302-0787
Michael RotherFakultät Biologie, Technische Universität Dresden, Dresden, Germany.ORCID 0000-0002-2306-8783

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In all domains of life, Archaea, Eukarya and Bacteria, the unusual amino acid selenocysteine (Sec) is co-translationally incorporated into proteins by recoding a UGA stop codon to a sense codon. A secondary structure on the mRNA, the selenocysteine insertion sequence (SECIS), is required, but its position, secondary structure and binding partner(s) are not conserved across the tree of life. Thus far, the nature of archaeal SECIS elements has been derived mainly from sequence analyses. A recently developed

Indexed as

MethanococcusMutagenesisSelenocysteine5' Untranslated RegionsBase SequenceCodon, TerminatorNucleic Acid ConformationRNA, Messenger5' Untranslated RegionsCodon, TerminatorRNA, MessengerSelenocysteineArchaeaMethanococcusreporterSECIS elementselenocysteine

Identifiers

PMID40000419
PMCPMC11881835

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.