Evidence map›Paper›PMID 40000278›Full record

ArticleBritish journal of anaesthesia2025

Does titration of anaesthesia using population-derived EEG indices overdose older patients?

Jamie W Sleigh

Abstract readEditorial
In one paragraph

Article in British journal of anaesthesia, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Jamie W SleighDepartment of Anaesthesia and Pain Medicine, Waikato Clinical School, University of Auckland, Hamilton, New Zealand. Electronic address: Jamie.sleigh@auckland.ac.nz.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Compared with the young, the older patient group has increased high-frequency EEG power whilst under volatile general anaesthesia. This increased high-frequency power elevates the spectral entropy values above the recommended range. Thus, aggressive titration of general anaesthesia with volatile agents to achieve entropy values of 40-60 in older patients will commonly result in overdose, as manifest by burst suppression.

Indexed as

Anesthesia, GeneralAnesthetics, InhalationDrug OverdoseElectroencephalographyAdultAgedAged, 80 and overAge FactorsHumansMiddle AgedAnesthetics, Inhalationagedepth of anaesthesiaEEGspectral entropyvolatile anaesthesia

Identifiers

PMID40000278
PMCPMC11947554

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.