Evidence map›Paper›PMID 40000218›Full record

ReviewSheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi2024

[Application of optogenetic technology in the research on olfactory bulb neural projection from advanced brain regions to regulate olfactory signal processing].

Tong Zhou, Yifan Wu, Meng Hu, Xin Tang, Ping Zhu, Liping Du, Chunsheng Wu

Abstract readReviewEnglish Abstract
In one paragraph

Review in Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Tong ZhouInstitute of Medical Engineering, Department of Biophysics, School of Basic Medicine, Xi'an Jiaotong University, Xi'an 710061, P. R. China.
Yifan WuInstitute of Medical Engineering, Department of Biophysics, School of Basic Medicine, Xi'an Jiaotong University, Xi'an 710061, P. R. China.
Meng HuInstitute of Medical Engineering, Department of Biophysics, School of Basic Medicine, Xi'an Jiaotong University, Xi'an 710061, P. R. China.
Xin TangInstitute of Medical Engineering, Department of Biophysics, School of Basic Medicine, Xi'an Jiaotong University, Xi'an 710061, P. R. China.
Ping ZhuInstitute of Medical Engineering, Department of Biophysics, School of Basic Medicine, Xi'an Jiaotong University, Xi'an 710061, P. R. China.
Liping DuInstitute of Medical Engineering, Department of Biophysics, School of Basic Medicine, Xi'an Jiaotong University, Xi'an 710061, P. R. China.
Chunsheng WuInstitute of Medical Engineering, Department of Biophysics, School of Basic Medicine, Xi'an Jiaotong University, Xi'an 710061, P. R. China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Olfactory bulb is a critical component in encoding and processing olfactory signals, characterized by its intricate neural projections and networks dedicated to this function. It has been found that descending neural projections from the olfactory cortex and other advanced brain regions can modulate the excitability of olfactory bulb output neurons in the olfactory bulb, either directly or indirectly, which can further influence olfactory discrimination, learning, and other abilities. In recent years, advancements in optogenetic technology have facilitated extensive application of neuron manipulation for studying neural circuits, thereby greatly accelerating research into olfactory mechanisms. This review summarizes the latest research progress on the regulatory effects of neural projections from the olfactory cortex, basal forebrain, raphe nucleus, and locus coeruleus on olfactory bulb function. Furthermore, the important role that photogenetic technology plays in olfactory mechanism research is evaluated. Finally, the existing problems and future development trends in current research are preliminarily proposed and explained. This review aims to provide new insights into the mechanisms underlying olfactory neural regulation as well as applications of optogenetic technology, which are crucial for advancing the research on olfactory mechanism and the application of optogenetic technology.

Indexed as

Olfactory BulbOlfactory PathwaysOptogeneticsSmellAnimalsHumansOlfactory CortexNeural circuitNeural projectionOlfactory bulbOlfactory signalPhotogenetics

Identifiers

PMID40000218
PMCPMC11955376

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.