Evidence map›Paper›PMID 40000079›Full record

SynthesisBMJ open2025

Role of informal carers in medication management for people with long-term conditions: a systematic review.

Maha Alkhaldi, Laura Lindsey, Charlotte Richardson

Abstract readSystematic Review
In one paragraph

Synthesis in BMJ open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
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  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Maha AlkhaldiSchool of Pharmacy, Newcastle University, Newcaslte Upon Tyne, UK.ORCID http://orcid.org/0009-0009-8537-9630
Laura LindseySchool of Pharmacy, Newcastle University, Newcaslte Upon Tyne, UK Laura.Lindsey@Newcastle.ac.uk.
Charlotte RichardsonSchool of Pharmacy, Newcastle University, Newcaslte Upon Tyne, UK.ORCID http://orcid.org/0000-0003-2195-4279

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo explore the literature about the role of unpaid informal carers in medication management for people with long-term conditions.

designSystematic review designed according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. INFORMATION SOURCE: MEDLINE (Ovid), Embase (Ovid), PsycINFO, Cumulated Index in Nursing and Allied Health Literature (EBSCO), Scopus and Web of Science were searched from inception until April 2024. Additional papers were identified by searching backwards and forwards the reference lists of included papers. ELIGIBILITY CRITERIA: Primary research studies were included if they reported medication-related activities undertaken by carers for people with long-term conditions. Qualitative and mixed methods studies were considered without restriction on language or country. DATA EXTRACTION AND SYNTHESIS: Relevant data were extracted and summarised in a table. The Mixed Method Appraisal Tool was used for quality assessment. Data were narratively synthesised.

resultsFrom 12 473 identified records, 107 underwent full text screening and 20 studies were included. Family carers were the predominant type of carer. Spouses and adult children constituted the largest caregiving dyads. Based on the required skills, two groups of roles were identified: physical roles, such as prescription management, and cognitive roles, such as decision-making. Carers used different strategies and tools to undertake medication-related activities including compliance aids and alarms. However, carers reported challenges in their experiences of caregiving, flagging up their need for additional support and education to commence such activities.

conclusionInformal carers undertake a wide variety of medication-related activities. The studies emphasised the need to support families as partners in health outcomes. This systematic review identifies the importance of bridging the gap between carers and healthcare providers. More efforts are needed to empower carers towards better and safer caregiving. Future work could address how to optimise carer involvement and engagement and provide best practice recommendations for carers' support. PROSPERO REGISTRATION NUMBER: CRD42024506694.

Indexed as

CaregiversMedication Therapy ManagementChronic DiseaseHumansCaregiversFamilyHealth Services AccessibilityPolypharmacySocial SupportSystematic Review

Identifiers

PMID40000079
PMCPMC12083308

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.