Longitudinally Predicting Behavioral Challenges From Executive Functioning in Youth With Down Syndrome.

Amanallah Soltani, Deborah J Fidler, Lina Patel, Kellie Voth, Anna J Esbensen

Abstract read

In one paragraph

Article in American journal on intellectual and developmental disabilities, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Amanallah SoltaniAmanallah Soltani, Taylor's University, Malaysia, Deborah J. Fidler, Colorado State University, Lina Patel, University of Colorado School of Medicine, Kellie Voth, Cincinnati Children's Hospital Medical Center, and Anna J. Esbensen, Cincinnati Children's Hospital Medical Center and University of Cincinnati College of Medicine.

Deborah J FidlerAmanallah Soltani, Taylor's University, Malaysia, Deborah J. Fidler, Colorado State University, Lina Patel, University of Colorado School of Medicine, Kellie Voth, Cincinnati Children's Hospital Medical Center, and Anna J. Esbensen, Cincinnati Children's Hospital Medical Center and University of Cincinnati College of Medicine.

Lina PatelAmanallah Soltani, Taylor's University, Malaysia, Deborah J. Fidler, Colorado State University, Lina Patel, University of Colorado School of Medicine, Kellie Voth, Cincinnati Children's Hospital Medical Center, and Anna J. Esbensen, Cincinnati Children's Hospital Medical Center and University of Cincinnati College of Medicine.

Kellie VothAmanallah Soltani, Taylor's University, Malaysia, Deborah J. Fidler, Colorado State University, Lina Patel, University of Colorado School of Medicine, Kellie Voth, Cincinnati Children's Hospital Medical Center, and Anna J. Esbensen, Cincinnati Children's Hospital Medical Center and University of Cincinnati College of Medicine.

Anna J EsbensenAmanallah Soltani, Taylor's University, Malaysia, Deborah J. Fidler, Colorado State University, Lina Patel, University of Colorado School of Medicine, Kellie Voth, Cincinnati Children's Hospital Medical Center, and Anna J. Esbensen, Cincinnati Children's Hospital Medical Center and University of Cincinnati College of Medicine.

Funding

INCLUDE19 – Evaluating outcome measures in young adults with Down syndromeR01HD093754 · NICHD · CINCINNATI CHILDRENS HOSP MED CTR · PI Anna J. Esbensen · 2018 to 2026

$6.2M

NICHD NIH HHS R01 HD093754

6 · The paper itself

Abstract

This study explored how caregiver-reported executive functioning domains, assessed by the BRIEF2 at baseline, predicted behavioral challenges reported by caregivers using the CBCL six months later. The sample included 94 youth with Down syndrome, aged 6 to 18 years. Results of hierarchical regression analyses revealed that, after controlling for the effect of IQ, working memory significantly predicted inattentive behaviors, inhibition significantly predicted rule-breaking behaviors, and both inhibition and emotional control significantly predicted aggressive and externalizing behaviors. After controlling for baseline behaviors, only working memory persisted as a significant predictor of inattentive behaviors measured six months later. The findings are discussed by referring to the relevant theories and research and providing clinical implications and recommendations for further studies.

Indexed as

AggressionDown SyndromeEmotional RegulationExecutive FunctionInhibition, PsychologicalMemory, Short-TermProblem BehaviorAdolescentChildFemaleHumansLongitudinal StudiesMalebehavioral challengesDown syndromeexecutive functioning

Identifiers

PMID39999868

DOI10.1352/1944-7558-130.2.146

PMCPMC12070328

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.